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    NOGC1 flavin containing monooxygenase FMO GS-OX-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842555, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NOGC1
    Official Full Name
    flavin containing monooxygenase FMO GS-OX-like protein
    Primary source
    TAIR:AT1G62580
    Locus tag
    AT1G62580
    See related
    Araport:AT1G62580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    nitric oxide-dependent guanylate cyclase 1; T3P18.14; T3P18_14
    Summary
    Encodes a flavin monooxygenase that binds NO, has a higher affinity for NO than for O(2) and can generate cGMP from GTP in vitro in an NO-dependent manner.
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    Genomic context

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    See NOGC1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (23173286..23176931)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene flavin-monooxygenase glucosinolate S-oxygenase 3 Neighboring gene flavin-monooxygenase glucosinolate S-oxygenase 4 Neighboring gene ncRNA Neighboring gene pentatricopeptide (PPR) repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Flavin-binding monooxygenase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel Arabidopsis thaliana nitric oxide-binding molecule with guanylate cyclase activity in vitro. Mulaudzi T, et al. FEBS Lett, 2011 Sep 2. PMID 21820435
    2. Nitrated cyclic GMP modulates guard cell signaling in Arabidopsis. Joudoi T, et al. Plant Cell, 2013 Feb. PMID 23396828, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001334039.1
    NM_001334040.1
    NM_104936.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N,N-dimethylaniline monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanylate cyclase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nitric oxide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxygen binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within stomatal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    flavin containing monooxygenase FMO GS-OX-like protein
    NP_176446.1
    • Flavin-binding monooxygenase family protein; FUNCTIONS IN: NADP or NADPH binding, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: intrinsic to endoplasmic reticulum membrane; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Dimethylaniline monooxygenase, N-oxide-forming (InterPro:IPR012143), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: Flavin-containing monooxygenase family protein (TAIR:AT1G63340.1); Has 12102 Blast hits to 11779 proteins in 1619 species: Archae - 69; Bacteria - 6462; Metazoa - 1123; Fungi - 1131; Plants - 751; Viruses - 0; Other Eukaryotes - 2566 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23173286..23176931
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104936.2 → NP_176446.1  flavin containing monooxygenase FMO GS-OX-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176446.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ELX9
      Conserved Domains (1) summary
      PLN02172
      Location:1 → 492
      PLN02172; flavin-containing monooxygenase FMO GS-OX

    2. NM_001334039.1 → NP_001321123.1  flavin containing monooxygenase FMO GS-OX-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HYU0, Q9SXD9
      UniProtKB/TrEMBL
      A0A654ELX9

    3. NM_001334040.1 → NP_001321124.1  flavin containing monooxygenase FMO GS-OX-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8APX2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SXD9.2

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