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    AKR2B ankyrin repeat-containing 2B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816246, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AKR2B
    Official Full Name
    ankyrin repeat-containing 2B
    Primary source
    TAIR:AT2G17390
    Locus tag
    AT2G17390
    See related
    Araport:AT2G17390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ankyrin repeat-containing 2B; F5J6.15; F5J6_15
    Summary
    Highly homologous to AKR2A. Involved in chloroplast biogenesis. Double mutants of AKR2A and AKR2B have yellow leaves, significantly reduced chloroplast proteins, and no thylakoid membranes.
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    Genomic context

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    See AKR2B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (7555586..7558064)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene 3-hydroxy-3-methylglutaryl-CoA reductase 2 Neighboring gene associated protein 19 Neighboring gene ARID/BRIGHT DNA-binding domain-containing protein Neighboring gene NADPH-dependent thioredoxin reductase A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants. Yang T, et al. J Biol Chem, 2002 Nov 22. PMID 12218065
    2. ANKYRIN REPEAT-CONTAINING PROTEIN 2A is an essential molecular chaperone for peroxisomal membrane-bound ASCORBATE PEROXIDASE3 in Arabidopsis. Shen G, et al. Plant Cell, 2010 Mar. PMID 20215589, Free PMC Article
    3. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_127294.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat-containing 2B
    NP_179331.1
    • ankyrin repeat-containing 2B (AKR2B); FUNCTIONS IN: transcription regulator activity; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ankyrin repeat-containing domain (InterPro:IPR020683), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: ankyrin repeat-containing protein 2 (TAIR:AT4G35450.1); Has 80350 Blast hits to 27630 proteins in 1286 species: Archae - 139; Bacteria - 6360; Metazoa - 42384; Fungi - 5488; Plants - 3518; Viruses - 784; Other Eukaryotes - 21677 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7555586..7558064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127294.5 → NP_179331.1  ankyrin repeat-containing 2B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179331.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q29Q26
      UniProtKB/TrEMBL
      A0A5S9WYY9, A0A654EYN8
      Conserved Domains (3) summary
      sd00045
      Location:252 → 283
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:225 → 316
      Ank_2; Ankyrin repeats (3 copies)
      cl17974
      Location:155 → 198
      STI1; STI1 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29Q26.1

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