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    CG10431 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35157, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10431provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032730
    Locus tag
    Dmel_CG10431
    See related
    AllianceGenome:FB:FBgn0032730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    dmCG10431; Dmel\CG10431
    Summary
    Predicted to enable chromatin insulator sequence binding activity and transcription cis-regulatory region binding activity. Involved in dendrite morphogenesis. Predicted to be located in nucleus. Predicted to be active in chromosome. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10431 in Genome Data Viewer
    Location:
    37B8-37B8; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18974710..18978187)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18974710..18978187)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Numb-associated kinase Neighboring gene Transport and Golgi organization 6 Neighboring gene L-2-hydroxyglutarate dehydrogenase Neighboring gene Swiprosin-1 Neighboring gene uncharacterized protein Neighboring gene ER membrane protein complex subunit 5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recurrent recruitment of the THAP DNA-binding domain and molecular domestication of the P-transposable element. Quesneville H, et al. Mol Biol Evol, 2005 Mar. PMID 15574804
    2. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Roussigne M, et al. Trends Biochem Sci, 2003 Feb. PMID 12575992
    3. The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Zhang P, et al. Proc Natl Acad Sci U S A, 2021 Feb 16. PMID 33558234, Free PMC Article
    4. Functional genomic analyses of two morphologically distinct classes of Drosophila sensory neurons: post-mitotic roles of transcription factors in dendritic patterning. Iyer EP, et al. PLoS One, 2013. PMID 23977298, Free PMC Article
    5. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin insulator sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10431-PA
    CG10431-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18974710..18978187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136080.3 → NP_609924.2  uncharacterized protein Dmel_CG10431, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609924.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6V0, Q9VJ27
      Conserved Domains (4) summary
      smart00868
      Location:123 → 192
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:677 → 697
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05485
      Location:4 → 81
      THAP; THAP domain
      pfam13912
      Location:674 → 700
      zf-C2H2_6; C2H2-type zinc finger

    2. NM_001299149.1 → NP_001286078.1  uncharacterized protein Dmel_CG10431, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286078.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6V0, Q9VJ27
      Conserved Domains (4) summary
      smart00868
      Location:123 → 192
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:677 → 697
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05485
      Location:4 → 81
      THAP; THAP domain
      pfam13912
      Location:674 → 700
      zf-C2H2_6; C2H2-type zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJ27 Q9VJ27

    Gene LinkOut

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