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    Cyp309a2 Cytochrome P450 309a2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33439, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp309a2provided by FlyBase
    Official Full Name
    Cytochrome P450 309a2provided by FlyBase
    Primary source
    FLYBASE:FBgn0041337
    Locus tag
    Dmel_CG18559
    See related
    AllianceGenome:FB:FBgn0041337
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    309a2; CG18559; Dmel\CG18559
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in gonad and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp309a2 in Genome Data Viewer
    Location:
    23A1-23A1; 2-7 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2564886..2573037, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2564886..2573037, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44113 Neighboring gene Cytochrome P450 309a1 Neighboring gene Radiation insensitive 1 Neighboring gene SWIM domain containing Srs2 interacting protein 1 Neighboring gene insensitive

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Retrotransposon-gene associations are widespread among D. melanogaster populations. Franchini LF, et al. Mol Biol Evol, 2004 Jul. PMID 15014149
    2. Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase. Radyuk SN, et al. Mech Ageing Dev, 2012 Jun. PMID 22579812
    3. Insensitive is a corepressor for Suppressor of Hairless and regulates Notch signalling during neural development. Duan H, et al. EMBO J, 2011 Jul 15. PMID 21765394, Free PMC Article
    4. Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms. Sujkowski A, et al. Aging (Albany NY), 2015 Aug. PMID 26298685, Free PMC Article
    5. Su(z)2 antagonizes auto-repression of Myc in Drosophila, increasing Myc levels and subsequent trans-activation. Khan A, et al. PLoS One, 2009. PMID 19333393, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 309a2
    Names
    CG18559-PA
    Cyp309a2-PA
    NP_608689.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2564886..2573037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134845.2 → NP_608689.2  cytochrome P450 309a2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608689.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82713, Q8T422, Q9VQD3
      Related
      FBpp0077428
      Conserved Domains (1) summary
      cl12078
      Location:70 → 526
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82713.2 P82713

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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