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    CG6414 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31352, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6414provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029690
    Locus tag
    Dmel_CG6414
    See related
    AllianceGenome:FB:FBgn0029690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6414
    Summary
    Predicted to enable carboxylesterase activity. Orthologous to human CES3 (carboxylesterase 3) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6414 in Genome Data Viewer
    Location:
    4A1-4A1; 1-6 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3968788..3971350, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3863026..3865383, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene lava lamp Neighboring gene antisense RNA:CR45481 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43298 Neighboring gene long non-coding RNA:CR45482

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Birth and death of genes and functions in the beta-esterase cluster of Drosophila. Robin C, et al. J Mol Evol, 2009 Jul. PMID 19536450, Free PMC Article
    2. Exploring the correlation between deltamethrin stress and Keap1-Nrf2-ARE pathway from Drosophila melanogaster RNASeq data. Liu Y, et al. Genomics, 2020 Mar. PMID 31376529
    3. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250
    4. Modeling spinal muscular atrophy in Drosophila. Chang HC, et al. PLoS One, 2008 Sep 15. PMID 18791638, Free PMC Article
    5. Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Klebes A, et al. Development, 2005 Aug. PMID 16077094

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carboxylesterase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6414-PA
    CG6414-PB
    NP_001303565.1
    NP_570089.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3968788..3971350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316636.1 → NP_001303565.1  uncharacterized protein Dmel_CG6414, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ17, Q9W4N5
      Conserved Domains (2) summary
      COG0657
      Location:116 → 254
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:36 → 567
      COesterase; Carboxylesterase family

    2. NM_130733.2 → NP_570089.1  uncharacterized protein Dmel_CG6414, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570089.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ17, Q9W4N5
      Related
      FBpp0070594
      Conserved Domains (2) summary
      COG0657
      Location:116 → 254
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:36 → 567
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZ17 Q8MZ17
    Q9W4N5 Q9W4N5

    Gene LinkOut

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