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    mRpS28 mitochondrial ribosomal protein S28 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37136, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRpS28provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein S28provided by FlyBase
    Primary source
    FLYBASE:FBgn0034361
    Locus tag
    Dmel_CG5497
    See related
    AllianceGenome:FB:FBgn0034361
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH13070; CG5497; Dmel\CG5497; MRP-S35; mrpS28
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial small ribosomal subunit. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; dorsal pharyngeal muscle cell; embryonic/larval midgut; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 47. Orthologous to human MRPS28 (mitochondrial ribosomal protein S28). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See mRpS28 in Genome Data Viewer
    Location:
    55E2-55E2; 2-86 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18614210..18615018, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14501715..14502523, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46271 Neighboring gene Rad, Gem/Kir family member 2 Neighboring gene Guanine nucleotide exchange factor in mesoderm Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Signatures of Drug Response Variability in Drosophila melanogaster. Rohde PD, et al. Genetics, 2019 Oct. PMID 31455722, Free PMC Article
    2. The mitochondrial ribosomal protein mRpL4 regulates Notch signaling. Mo D, et al. EMBO Rep, 2023 Jun 5. PMID 37009823, Free PMC Article
    3. Transcriptional responses to hyperplastic MRL signalling in Drosophila. Jonchère V, et al. Open Biol, 2017 Feb. PMID 28148822, Free PMC Article
    4. Comparative genomics analysis of metallothioneins in twelve Drosophila species. Guirola M, et al. J Inorg Biochem, 2011 Aug. PMID 21726767
    5. Drosophila follicle stem cells are regulated by proliferation and niche adhesion as well as mitochondria and ROS. Wang ZA, et al. Nat Commun, 2012 Apr 3. PMID 22473013, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein S28
    Names
    CG5497-PA
    mRpS28-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18614210..18615018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079061.4 → NP_523785.2  mitochondrial ribosomal protein S28 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523785.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBA5, Q8SX15
      Related
      FBpp0085893
      Conserved Domains (1) summary
      pfam10246
      Location:76 → 180
      MRP-S35; Mitochondrial ribosomal protein MRP-S35
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBA5 A1ZBA5
    Q8SX15 Q8SX15

    Gene LinkOut

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