bic bicaudal [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: bicprovided by FlyBase
Official Full Name: bicaudalprovided by FlyBase
Primary source: FLYBASE:FBgn0000181
Locus tag: Dmel_CG3644
See related: AllianceGenome:FB:FBgn0000181
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 107/12; 5A; BcDNA.GM05329; BcDNA:GM05329; Bic; Btf; BTF3; CG3644; Dmel\CG3644; E(2)Bic; E(Bic); l(2)49Da; l(2)k10712; l(2)vr22; NAC-beta; vr22
Summary: Involved in several processes, including anterior/posterior axis specification; embryonic development via the syncytial blastoderm; and regulation of pole plasm oskar mRNA localization. Predicted to be part of nascent polypeptide-associated complex. Predicted to be active in cytosol. Is expressed in several structures, including adult head; adult heart; female germline cell; larval somatic muscle cell; and mesoderm. Orthologous to several human genes including BTF3L4 (basic transcription factor 3 like 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (12870249..12871794)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (8757754..8759299)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in embryonic development via the syncytial blastoderm	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular mRNA localization involved in anterior/posterior axis specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pole plasm protein localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein transport	TAS Traceable Author Statement more info	PubMed
involved_in regulation of establishment of protein localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of pole plasm oskar mRNA localization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of nascent polypeptide-associated complex	IBA Inferred from Biological aspect of Ancestor more info
part_of nascent polypeptide-associated complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed