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    CG10081 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37226, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10081provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034441
    Locus tag
    Dmel_CG10081
    See related
    AllianceGenome:FB:FBgn0034441
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10081
    Summary
    Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10081 in Genome Data Viewer
    Location:
    56D2-56D3; 2-89 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19385923..19389318)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15273428..15276823)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Succinate dehydrogenase, subunit A (flavoprotein) Neighboring gene antisense RNA:CR45925 Neighboring gene crammer

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Seizure suppression by gain-of-function escargot mutations. Hekmat-Scafe DS, et al. Genetics, 2005 Mar. PMID 15654097, Free PMC Article
    2. The transcriptional diversity of 25 Drosophila cell lines. Cherbas L, et al. Genome Res, 2011 Feb. PMID 21177962, Free PMC Article
    3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10081-PA
    CG10081-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19385923..19389318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137574.3 → NP_611418.1  uncharacterized protein Dmel_CG10081, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611418.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V5E4
      Related
      FBpp0085712
      Conserved Domains (1) summary
      cd03875
      Location:72 → 379
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

    2. NM_001274162.1 → NP_001261091.1  uncharacterized protein Dmel_CG10081, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261091.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KG92
      Conserved Domains (1) summary
      cd03875
      Location:72 → 379
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KG92 A0A0B4KG92
    Q4V5E4 Q4V5E4

    Gene LinkOut

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