U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cm carmine [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31647, updated on 9-Dec-2024

    Summary

    Official Symbol
    cmprovided by FlyBase
    Official Full Name
    carmineprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000330
    Locus tag
    Dmel_CG3035
    See related
    AllianceGenome:FB:FBgn0000330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ap-3; AP-3; AP-3mu; AP3mu3; apm3; cg3035; CG3035; CG32731; Dmel\CG3035; Dmu3; l(1)VEM119; mu3; Mu3
    Summary
    Predicted to enable cargo adaptor activity. Involved in several processes, including Notch receptor processing; determination of adult lifespan; and exocytosis. Predicted to be part of AP-3 adaptor complex. Predicted to be active in cytoplasmic vesicle. Orthologous to several human genes including AP3M2 (adaptor related protein complex 3 subunit mu 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    6E4-6E4; 1-18 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7009006..7011145, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6903039..6905178, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43837 Neighboring gene Innexin 2 Neighboring gene sloth 1 Neighboring gene sloth 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cargo adaptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in Notch receptor processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in exocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    carmine
    Names
    CG3035-PA
    CG3035-PB
    adaptor protein complex 3, mu subunit
    cm-PA
    cm-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7009006..7011145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272373.1NP_001259302.1  carmine, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259302.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76928
      Conserved Domains (1) summary
      cl10970
      Location:163414
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    2. NM_176700.3NP_788873.1  carmine, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788873.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76928
      Related
      FBpp0070992
      Conserved Domains (1) summary
      cl10970
      Location:163414
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)