Inx7 Innexin 7 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Inx7provided by FlyBase
Official Full Name: Innexin 7provided by FlyBase
Primary source: FLYBASE:FBgn0027106
Locus tag: Dmel_CG2977
See related: AllianceGenome:FB:FBgn0027106
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG2977; CG32731; D-inx-7; Dm-inx7; Dmel\CG2977; FBpp0070994; inx-7; inx7; prp7
Summary: Predicted to enable gap junction channel activity. Involved in medium-term memory. Located in cytoplasm; gap junction; and nucleus. Is expressed in adult brain; adult head; embryonic midgut constriction; embryonic/larval midgut; and synaptic neuropil domain. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (6991612..6993612, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (6885645..6903902, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Plays an essential role in axon guidance and embryonic nervous system development.
Title: The Drosophila innexin 7 gap junction protein is required for development of the embryonic nervous system.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables gap junction channel activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intercellular transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in medium-term memory	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phototransduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in gap junction	IBA Inferred from Biological aspect of Ancestor more info
located_in gap junction	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info