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    CG17544 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35213, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17544provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032775
    Locus tag
    Dmel_CG17544
    See related
    AllianceGenome:FB:FBgn0032775
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17544
    Summary
    Predicted to enable fatty acid binding activity; flavin adenine dinucleotide binding activity; and pristanoyl-CoA oxidase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase. Located in peroxisome. Is expressed in several structures, including adult head; dorsal sensory complex primordium; dorsal sensory complex proper primordium; embryonic hindgut; and ganglia. Orthologous to human ACOX3 (acyl-CoA oxidase 3, pristanoyl). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17544 in Genome Data Viewer
    Location:
    37D4-37D5; 2-54 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19390370..19398493, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19390370..19398493, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene fondue Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 359 Neighboring gene Paxillin Neighboring gene Galactose-specific C-type lectin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila. Pandey M, et al. Elife, 2021 Jun 8. PMID 34100717, Free PMC Article
    2. Downstream of identity genes: muscle-type-specific regulation of the fusion process. Bataillé L, et al. Dev Cell, 2010 Aug 17. PMID 20708593, Free PMC Article
    3. Cardiac Snail family of transcription factors directs systemic lipid metabolism in Drosophila. Liu Y, et al. PLoS Genet, 2019 Nov. PMID 31725726, Free PMC Article
    4. An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Kanca O, et al. Elife, 2019 Nov 1. PMID 31674908, Free PMC Article
    5. GMAP is an Atg8a-interacting protein that regulates Golgi turnover in Drosophila. Rahman A, et al. Cell Rep, 2022 May 31. PMID 35649355, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyl-CoA oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyl-CoA oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables fatty acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pristanoyl-CoA oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in fatty acid beta-oxidation using acyl-CoA oxidase IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid beta-oxidation using acyl-CoA oxidase IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17544-PA
    CG17544-PB
    CG17544-PC
    CG17544-PD
    NP_001163015.1
    NP_609961.2
    NP_724180.1
    NP_724181.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19390370..19398493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136117.4 → NP_609961.2  uncharacterized protein Dmel_CG17544, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609961.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TH0, Q9VIX4
      Related
      FBpp0080757
      Conserved Domains (2) summary
      cd01150
      Location:16 → 670
      AXO; Peroxisomal acyl-CoA oxidase
      PLN02443
      Location:18 → 687
      PLN02443; acyl-coenzyme A oxidase

    2. NM_001169544.2 → NP_001163015.1  uncharacterized protein Dmel_CG17544, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163015.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TH0, Q9VIX4
      Conserved Domains (2) summary
      cd01150
      Location:16 → 670
      AXO; Peroxisomal acyl-CoA oxidase
      PLN02443
      Location:18 → 687
      PLN02443; acyl-coenzyme A oxidase

    3. NM_165291.3 → NP_724181.1  uncharacterized protein Dmel_CG17544, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724181.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TH0, Q9VIX4
      Related
      FBpp0080758
      Conserved Domains (2) summary
      cd01150
      Location:16 → 670
      AXO; Peroxisomal acyl-CoA oxidase
      PLN02443
      Location:18 → 687
      PLN02443; acyl-coenzyme A oxidase

    4. NM_165290.4 → NP_724180.1  uncharacterized protein Dmel_CG17544, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724180.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TH0, Q9VIX4
      Related
      FBpp0080759
      Conserved Domains (2) summary
      cd01150
      Location:16 → 670
      AXO; Peroxisomal acyl-CoA oxidase
      PLN02443
      Location:18 → 687
      PLN02443; acyl-coenzyme A oxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95TH0 Q95TH0
    Q9VIX4 Q9VIX4

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