Wdr82 WD repeat domain 82 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Wdr82provided by RGD
Official Full Name: WD repeat domain 82provided by RGD
Primary source: RGD:1584269
See related: EnsemblRapid:ENSRNOG00000048441 AllianceGenome:RGD:1584269
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in RNA catabolic process and negative regulation of DNA-templated transcription. Predicted to be located in chromatin; chromosome, telomeric region; and nucleolus. Predicted to be part of PTW/PP1 phosphatase complex and Set1C/COMPASS complex. Orthologous to human WDR82 (WD repeat domain 82). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 250.9), Thymus (RPKM 227.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q32

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (115693297..115713262)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (106814569..106834535)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (114866769..114886208)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription termination	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
involved_in lncRNA catabolic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of DNA-templated transcription, elongation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of lncRNA transcription	ISO Inferred from Sequence Orthology more info
involved_in nuclear RNA surveillance	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of PTW/PP1 phosphatase complex	ISO Inferred from Sequence Orthology more info
part_of Set1C/COMPASS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Set1C/COMPASS complex	ISO Inferred from Sequence Orthology more info
located_in chromatin	ISO Inferred from Sequence Orthology more info
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
part_of histone methyltransferase complex	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: WD repeat-containing protein 82

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271306.1 → NP_001258235.1 WD repeat-containing protein 82

See identical proteins and their annotated locations for NP_001258235.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

A0A096MJB3, A0A8I6AN51, A6I2P5

Related

ENSRNOP00000095017.2, ENSRNOT00000096974.2

Conserved Domains (2) summary

cd00200
Location:15 → 300

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:24 → 61

7WD40; WD40 repeat [structural motif]