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    Zfp414 zinc finger protein 414 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299647, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp414provided by RGD
    Official Full Name
    zinc finger protein 414provided by RGD
    Primary source
    RGD:1308123
    See related
    EnsemblRapid:ENSRNOG00000008378 AllianceGenome:RGD:1308123
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf414; RGD1308123
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Orthologous to human ZNF414 (zinc finger protein 414). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 66.3), Thymus (RPKM 55.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp414 in Genome Data Viewer
    Location:
    7q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (15122408..15125115)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (14420232..14422939)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (18497795..18500492)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 10 Neighboring gene uncharacterized LOC120093540 Neighboring gene myosin IF Neighboring gene BAF nuclear assembly factor 1, pseudogene 1 Neighboring gene PML-RARA regulated adaptor molecule 1 Neighboring gene heterogeneous nuclear ribonucleoprotein M Neighboring gene membrane associated ring-CH-type finger 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105571

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 414

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009664.2 → NP_001009664.1  zinc finger protein 414 isoform 2

      See identical proteins and their annotated locations for NP_001009664.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q5PPH4
      UniProtKB/TrEMBL
      A0A8L2UIH2, A6KQG8
      Related
      ENSRNOP00000011094.5, ENSRNOT00000011094.8
      Conserved Domains (2) summary
      sd00017
      Location:104 → 123
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:100 → 194
      zf-C2H2_8; C2H2-type zinc ribbon

    2. NM_001393832.1 → NP_001380761.1  zinc finger protein 414 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8L2UIH2
      Conserved Domains (2) summary
      sd00017
      Location:116 → 135
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:112 → 206
      zf-C2H2_8; C2H2-type zinc ribbon

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      15122408..15125115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063263191.1 → XP_063119261.1  zinc finger protein 414 isoform X4

    2. XM_006241119.5 → XP_006241181.1  zinc finger protein 414 isoform X2

      See identical proteins and their annotated locations for XP_006241181.1

      UniProtKB/TrEMBL
      A0A8L2UIH2, A6KQG7
      Conserved Domains (2) summary
      sd00017
      Location:104 → 123
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:100 → 194
      zf-C2H2_8; C2H2-type zinc ribbon

    3. XM_063263190.1 → XP_063119260.1  zinc finger protein 414 isoform X3

    4. XM_006241117.5 → XP_006241179.1  zinc finger protein 414 isoform X1

      UniProtKB/TrEMBL
      A0A8L2UIH2
      Conserved Domains (2) summary
      sd00017
      Location:116 → 135
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:112 → 206
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5PPH4.1 GenPept UniProtKB/Swiss-Prot:Q5PPH4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
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