Coq7 Coenzyme Q7 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Coq7provided by FlyBase
Official Full Name: Coenzyme Q7provided by FlyBase
Primary source: FLYBASE:FBgn0029502
Locus tag: Dmel_CG14437
See related: AllianceGenome:FB:FBgn0029502
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14437; COQ7; Dclk1; Dmel\CG14437
Summary: Predicted to enable 3-demethoxyubiquinol 3-hydroxylase activity. Predicted to be involved in several processes, including determination of adult lifespan; regulation of reactive oxygen species metabolic process; and ubiquinone biosynthetic process. Predicted to be part of ubiquinone biosynthesis complex. Predicted to be active in mitochondrial inner membrane and nucleus. Is expressed in adult head. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 9 and primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (6771225..6773039)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (6665258..6667072)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 3-demethoxyubiquinol 3-hydroxylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in determination of adult lifespan	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of reactive oxygen species metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of ubiquinone biosynthesis complex	ISS Inferred from Sequence or Structural Similarity more info