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    laf labial associated factor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40606, updated on 18-Sep-2024

    Summary

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    Official Symbol
    lafprovided by FlyBase
    Official Full Name
    labial associated factorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0020280
    Locus tag
    Dmel_CG14660
    See related
    AllianceGenome:FB:FBgn0020280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    C6; CG14660; Dmel\CG14660
    Orthologs
    all
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    Genomic context

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    See laf in Genome Data Viewer
    Location:
    82E1-82E1; 3-47.1 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4876005..4878533, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (701727..704255, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene odd paired Neighboring gene long non-coding RNA:CR45580 Neighboring gene Germ line transcription factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Peng JC, et al. Nat Genet, 2016 Mar. PMID 26780607, Free PMC Article
    2. Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Moshkin YM, et al. Mol Cell, 2009 Sep 24. PMID 19782028
    3. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    labial associated factor
    Names
    CG14660-PA
    CG14660-PB
    clone C6
    laf-PA
    laf-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4876005..4878533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141247.1 → NP_649504.1  labial associated factor, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649504.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8Z9, Q9VN67
      Related
      FBpp0078492, FBtr0078852

    2. NM_001300236.1 → NP_001287165.1  labial associated factor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287165.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGL3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LGL3 A0A0B4LGL3
    Q8T8Z9 Q8T8Z9

    Gene LinkOut

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