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    CG7386 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38719, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7386provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035691
    Locus tag
    Dmel_CG7386
    See related
    AllianceGenome:FB:FBgn0035691
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7386
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7386 in Genome Data Viewer
    Location:
    65A7-65A8; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6189745..6192049)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6182845..6185149)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene D19B Neighboring gene uncharacterized protein Neighboring gene D19A Neighboring gene Splicing factor 3b subunit 6 Neighboring gene Transportin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1. Guven-Ozkan T, et al. Cell Rep, 2016 Feb 23. PMID 26876166, Free PMC Article
    2. Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila. Bonchuk A, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33638995, Free PMC Article
    3. HR repair pathway plays a crucial role in maintaining neural stem cell fate under irradiation stress. Xu X, et al. Life Sci Alliance, 2023 Aug. PMID 37197982, Free PMC Article
    4. Genome-wide patterns of local adaptation in Western European Drosophila melanogaster natural populations. Mateo L, et al. Sci Rep, 2018 Nov 1. PMID 30385770, Free PMC Article
    5. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7386-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6189745..6192049
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139779.3 → NP_648036.1  uncharacterized protein Dmel_CG7386 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648036.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWF1, Q9VRV6
      Related
      FBpp0076707
      Conserved Domains (3) summary
      smart00868
      Location:10 → 81
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:534 → 555
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:575 → 600
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AWF1 Q6AWF1
    Q9VRV6 Q9VRV6

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