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    Dbp73D Dead box protein 73D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39871, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dbp73Dprovided by FlyBase
    Official Full Name
    Dead box protein 73Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004556
    Locus tag
    Dmel_CG9680
    See related
    AllianceGenome:FB:FBgn0004556
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9680; DBP73D; DDX51; Dmel\CG9680; DmRH7
    Summary
    Predicted to enable ATP binding activity and nucleic acid binding activity. Predicted to be active in nucleus. Is expressed in adult head; egg chamber; nurse cell; and organism. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dbp73D in Genome Data Viewer
    Location:
    73C1-73C1; 3-44 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16728496..16730818, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16721596..16723918, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Peptidoglycan recognition protein SB2 Neighboring gene Peptidoglycan recognition protein SB1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dbp73D, a Drosophila gene expressed in ovary, encodes a novel D-E-A-D box protein. Patterson LF, et al. Nucleic Acids Res, 1992 Jun 25. PMID 1620603, Free PMC Article
    2. Gene expression differences consistent with water loss reduction underlie desiccation tolerance of natural Drosophila populations. Horváth V, et al. BMC Biol, 2023 Feb 16. PMID 36797754, Free PMC Article
    3. A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans. Eisen A, et al. Biochim Biophys Acta, 1998 Apr 29. PMID 9565667
    4. Changes in Drosophila melanogaster midgut proteins in response to dietary Bowman-Birk inhibitor. Li HM, et al. Insect Mol Biol, 2007 Oct. PMID 17725801
    5. Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function. Zaidman-Rémy A, et al. PLoS One, 2011 Feb 18. PMID 21364998, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dead box protein 73D
    Names
    CG9680-PA
    Dbp73D-PA
    dead box protein 73
    NP_476833.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16728496..16730818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057485.4 → NP_476833.1  dead box protein 73D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476833.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P26802, Q9XZ18
      Related
      FBpp0075106
      Conserved Domains (3) summary
      PRK11192
      Location:149 → 629
      PRK11192; ATP-dependent RNA helicase SrmB; Provisional
      cd00079
      Location:418 → 551
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:162 → 370
      DEAD; DEAD/DEAH box helicase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26802.3 P26802

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