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    NTN4 netrin 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712628, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NTN4provided by VGNC
    Official Full Name
    netrin 4provided by VGNC
    Primary source
    VGNC:VGNC:75399
    See related
    Ensembl:ENSMMUG00000000521
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NTN4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (95467087..95595682, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (95515341..95644153, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene methionyl aminopeptidase 2 Neighboring gene ubiquitin specific peptidase 44 Neighboring gene phosphoglycerate mutase 1-like Neighboring gene uncharacterized LOC114670924 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC107000979 Neighboring gene uncharacterized LOC114670926

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in basement membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of laminin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    netrin-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266055.1 → NP_001252984.1  netrin-4 precursor

      See identical proteins and their annotated locations for NP_001252984.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047827
      UniProtKB/TrEMBL
      F7A3Z5, F7A403, H9F758
      Related
      ENSMMUP00000000709.2, ENSMMUT00000000766.3
      Conserved Domains (4) summary
      cd00055
      Location:261 → 320
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:516 → 626
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      pfam00053
      Location:395 → 449
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:43 → 260
      Laminin_N; Laminin N-terminal (Domain VI)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      95467087..95595682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828961.1 → XP_028684794.1  netrin-4 isoform X1

      UniProtKB/TrEMBL
      H9F758
      Conserved Domains (4) summary
      cd00055
      Location:224 → 283
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:479 → 589
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      pfam00053
      Location:358 → 412
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:6 → 223
      Laminin_N; Laminin N-terminal (Domain VI)

    2. XM_015152395.2 → XP_015007881.1  netrin-4 isoform X1

      UniProtKB/TrEMBL
      H9F758
      Conserved Domains (4) summary
      cd00055
      Location:224 → 283
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:479 → 589
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      pfam00053
      Location:358 → 412
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:6 → 223
      Laminin_N; Laminin N-terminal (Domain VI)
    Nucleotide Protein
    Heading Accession and Version

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