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    SETD2 SET domain containing 2, histone lysine methyltransferase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711825, updated on 17-Aug-2024

    Summary

    Official Symbol
    SETD2provided by VGNC
    Official Full Name
    SET domain containing 2, histone lysine methyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:77269
    See related
    Ensembl:ENSMMUG00000021117
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See SETD2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (103009809..103161428, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (95405980..95516712)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676342 Neighboring gene neurobeachin like 2 Neighboring gene small nucleolar RNA U13 Neighboring gene kinesin family member 9 Neighboring gene kelch like family member 18 Neighboring gene protein tyrosine phosphatase non-receptor type 23

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K36 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase SETD2
    XP_028699892.1
    XP_028699893.1
    XP_028699894.1
    XP_028699895.1
    XP_028699896.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      103009809..103161428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028844063.1XP_028699896.1  histone-lysine N-methyltransferase SETD2 isoform X5

      UniProtKB/TrEMBL
      H9FTE9
      Conserved Domains (6) summary
      smart00570
      Location:14961550
      AWS; associated with SET domains
      smart00317
      Location:15511674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:16751691
      PostSET; Cysteine-rich motif following a subset of SET domains
      TIGR01622
      Location:17071826
      SF-CC1; splicing factor, CC1-like family
      pfam08236
      Location:21632250
      SRI; SRI (Set2 Rpb1 interacting) domain
      pfam00397
      Location:20852114
      WW; WW domain
    2. XM_028844062.1XP_028699895.1  histone-lysine N-methyltransferase SETD2 isoform X4

      UniProtKB/TrEMBL
      H9FTE9
      Conserved Domains (5) summary
      smart00570
      Location:14961550
      AWS; associated with SET domains
      smart00317
      Location:15511674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:16751691
      PostSET; Cysteine-rich motif following a subset of SET domains
      pfam08236
      Location:21642251
      SRI; SRI (Set2 Rpb1 interacting) domain
      pfam00397
      Location:20862115
      WW; WW domain
    3. XM_028844061.1XP_028699894.1  histone-lysine N-methyltransferase SETD2 isoform X3

      UniProtKB/TrEMBL
      A0A5F8ARP5, H9FTE9
      Related
      ENSMMUP00000080068.1, ENSMMUT00000100792.1
      Conserved Domains (6) summary
      pfam05279
      Location:18962079
      Asp-B-Hydro_N; Aspartyl beta-hydroxylase N-terminal region
      smart00570
      Location:14961550
      AWS; associated with SET domains
      smart00317
      Location:15511674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:16751691
      PostSET; Cysteine-rich motif following a subset of SET domains
      pfam08236
      Location:24252512
      SRI; SRI (Set2 Rpb1 interacting) domain
      pfam00397
      Location:23472376
      WW; WW domain
    4. XM_028844060.1XP_028699893.1  histone-lysine N-methyltransferase SETD2 isoform X2

      UniProtKB/TrEMBL
      H9FTE9
      Conserved Domains (6) summary
      pfam05279
      Location:19412123
      Asp-B-Hydro_N; Aspartyl beta-hydroxylase N-terminal region
      smart00570
      Location:14961550
      AWS; associated with SET domains
      smart00317
      Location:15511674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:16751691
      PostSET; Cysteine-rich motif following a subset of SET domains
      pfam08236
      Location:24692556
      SRI; SRI (Set2 Rpb1 interacting) domain
      pfam00397
      Location:23912420
      WW; WW domain
    5. XM_028844059.1XP_028699892.1  histone-lysine N-methyltransferase SETD2 isoform X1

      UniProtKB/TrEMBL
      F7HU62, H9FTE9
      Related
      ENSMMUP00000027795.4, ENSMMUT00000029698.4
      Conserved Domains (6) summary
      pfam05279
      Location:19412124
      Asp-B-Hydro_N; Aspartyl beta-hydroxylase N-terminal region
      smart00570
      Location:14961550
      AWS; associated with SET domains
      smart00317
      Location:15511674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:16751691
      PostSET; Cysteine-rich motif following a subset of SET domains
      pfam08236
      Location:24702557
      SRI; SRI (Set2 Rpb1 interacting) domain
      pfam00397
      Location:23922421
      WW; WW domain

    RNA

    1. XR_003727278.1 RNA Sequence

    2. XR_003727277.1 RNA Sequence

    3. XR_003727279.1 RNA Sequence