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    ASB3 ankyrin repeat and SOCS box containing 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716503, updated on 5-Mar-2024

    Summary

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    Gene symbol
    ASB3
    Gene description
    ankyrin repeat and SOCS box containing 3
    See related
    Ensembl:ENSMMUG00000010634
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ASB3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (54890102..55016938)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (54554258..54680735, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene G protein-coupled receptor 75 Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene syncytin-1-like Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene U6 spliceosomal RNA Neighboring gene transcription initiation factor TFIID subunit 9-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205031.3 → NP_001191960.2  ankyrin repeat and SOCS box protein 3

      Status: PROVISIONAL

      Source sequence(s)
      CB229909, QNVO02000094
      UniProtKB/TrEMBL
      A0A5F7ZMQ7
      Related
      ENSMMUP00000013939.4, ENSMMUT00000014879.4
      Conserved Domains (3) summary
      PHA03095
      Location:6 → 235
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:384 → 434
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      54890102..55016938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028831630.1 → XP_028687463.1  ankyrin repeat and SOCS box protein 3 isoform X3

      UniProtKB/TrEMBL
      F7BJ78
      Conserved Domains (4) summary
      PHA03095
      Location:13 → 264
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:477 → 527
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:164 → 194
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:234 → 327
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_028831636.1 → XP_028687469.1  ankyrin repeat and SOCS box protein 3 isoform X7

      UniProtKB/TrEMBL
      F7BJ78
      Conserved Domains (4) summary
      PHA03100
      Location:22 → 237
      PHA03100; ankyrin repeat protein; Provisional
      cd03722
      Location:459 → 509
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:216 → 309
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_028831631.1 → XP_028687464.1  ankyrin repeat and SOCS box protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A5G0, F7BJ78
      Related
      ENSMMUP00000072261.1, ENSMMUT00000095063.1
      Conserved Domains (4) summary
      PHA03100
      Location:22 → 237
      PHA03100; ankyrin repeat protein; Provisional
      cd03722
      Location:457 → 507
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:216 → 309
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_028831635.1 → XP_028687468.1  ankyrin repeat and SOCS box protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZMQ7, F7BJ60
      Conserved Domains (3) summary
      PHA03095
      Location:6 → 235
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:384 → 434
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]

    5. XM_028831634.1 → XP_028687467.1  ankyrin repeat and SOCS box protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZMQ7, F7BJ60
      Conserved Domains (3) summary
      PHA03095
      Location:6 → 235
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:384 → 434
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]

    6. XM_028831632.1 → XP_028687465.1  ankyrin repeat and SOCS box protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A5F7ZMQ7
      Conserved Domains (3) summary
      PHA03095
      Location:6 → 235
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:386 → 436
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]

    7. XM_028831633.1 → XP_028687466.1  ankyrin repeat and SOCS box protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A5F7ZMQ7
      Conserved Domains (3) summary
      PHA03095
      Location:6 → 235
      PHA03095; ankyrin-like protein; Provisional
      cd03722
      Location:386 → 436
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]

    8. XM_028831628.1 → XP_028687461.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A5F7Z8P5
      Conserved Domains (4) summary
      PHA03100
      Location:53 → 268
      PHA03100; ankyrin repeat protein; Provisional
      cd03722
      Location:490 → 540
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:177 → 207
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:247 → 340
      Ank_2; Ankyrin repeats (3 copies)

    9. XM_028831629.1 → XP_028687462.1  ankyrin repeat and SOCS box protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A5F7Z8P5
      Conserved Domains (4) summary
      PHA03100
      Location:53 → 268
      PHA03100; ankyrin repeat protein; Provisional
      cd03722
      Location:488 → 538
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:177 → 207
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:247 → 340
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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