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    SIRT5 sirtuin 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700855, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SIRT5provided by VGNC
    Official Full Name
    sirtuin 5provided by VGNC
    Primary source
    VGNC:VGNC:77485
    See related
    Ensembl:ENSMMUG00000008678
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SIRT5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (156384675..156434900, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (13793042..13886714)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene RAN binding protein 9 Neighboring gene U7 small nuclear RNA Neighboring gene nucleolar protein 7 Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene uncharacterized LOC114677702 Neighboring gene 40S ribosomal protein S4, X isoform-like Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and biomedical insights from the rhesus macaque genome. Rhesus Macaque Genome Sequencing and Analysis Consortium, et al. Science, 2007 Apr 13. PMID 17431167
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+ binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-malonyllysine demalonylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-succinyllysine desuccinylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NAD-dependent protein deacylase sirtuin-5, mitochondrial
    Names
    Regulatory protein SIR2 homolog 5
    SIR2-like protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      156384675..156434900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135582.2 → XP_014991068.2  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X4

      UniProtKB/Swiss-Prot
      F7EZ75
      UniProtKB/TrEMBL
      A0A1I7Q462, A0A5S6R6Z0, A0A8J8YRE7, F7EZ86, G7MQR7
      Related
      ENSMMUP00000080832.1, ENSMMUT00000102539.1
      Conserved Domains (1) summary
      cd01412
      Location:51 → 301
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    2. XM_015135578.2 → XP_014991064.2  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X4

      UniProtKB/Swiss-Prot
      F7EZ75
      UniProtKB/TrEMBL
      A0A1I7Q462, A0A5S6R6Z0, A0A8J8YRE7, F7EZ86, G7MQR7
      Related
      ENSMMUP00000060977.2, ENSMMUT00000070701.2
      Conserved Domains (1) summary
      cd01412
      Location:51 → 301
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    3. XM_028847830.1 → XP_028703663.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X2

      UniProtKB/Swiss-Prot
      F7EZ75
      UniProtKB/TrEMBL
      F7EZ68
      Related
      ENSMMUP00000011383.4, ENSMMUT00000012134.4
      Conserved Domains (1) summary
      cd01412
      Location:51 → 339
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    4. XM_015135579.2 → XP_014991065.2  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X4

      UniProtKB/Swiss-Prot
      F7EZ75
      UniProtKB/TrEMBL
      A0A1I7Q462, A0A5S6R6Z0, A0A8J8YRE7, F7EZ86, G7MQR7
      Related
      ENSMMUP00000011382.4, ENSMMUT00000012133.4
      Conserved Domains (1) summary
      cd01412
      Location:51 → 301
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    5. XM_028847829.1 → XP_028703662.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    6. XM_028847828.1 → XP_028703661.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    7. XM_028847833.1 → XP_028703666.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X3

      UniProtKB/Swiss-Prot
      F7EZ75
      Conserved Domains (1) summary
      cd01412
      Location:51 → 285
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    8. XM_028847832.1 → XP_028703665.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X3

      UniProtKB/Swiss-Prot
      F7EZ75
      Conserved Domains (1) summary
      cd01412
      Location:51 → 285
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    9. XM_028847826.1 → XP_028703659.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    10. XM_028847827.1 → XP_028703660.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    11. XM_028847824.1 → XP_028703657.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    12. XM_028847825.1 → XP_028703658.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01412
      Location:51 → 323
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    13. XM_028847831.1 → XP_028703664.1  NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X3

      UniProtKB/Swiss-Prot
      F7EZ75
      Conserved Domains (1) summary
      cd01412
      Location:51 → 285
      SIRT5_Af1_CobB; Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD ...

    RNA

    1. XR_003729131.1 RNA Sequence

    2. XR_003729129.1 RNA Sequence

    3. XR_003729130.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F7EZ75.1 GenPept UniProtKB/Swiss-Prot:F7EZ75

    Gene LinkOut

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