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    GLS2 glutaminase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712962, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GLS2provided by VGNC
    Official Full Name
    glutaminase 2provided by VGNC
    Primary source
    VGNC:VGNC:73035
    See related
    Ensembl:ENSMMUG00000000860
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GLS2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (56059666..56078503, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (55266701..55285023, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene timeless circadian regulator Neighboring gene major intrinsic protein of lens fiber Neighboring gene SPRY domain containing 4 Neighboring gene heat shock 60kDa protein 1 (chaperonin) pseudogene Neighboring gene RNA binding motif single stranded interacting protein 2 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutaminase liver isoform, mitochondrial
    Names
    glutaminase 2 (liver, mitochondrial)
    XP_001115245.1
    XP_015007501.1
    XP_015007502.1
    XP_028685447.1
    XP_028685448.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      56059666..56078503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001115245.4 → XP_001115245.1  glutaminase liver isoform, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0A7, F7H7H2
      Related
      ENSMMUP00000039396.3, ENSMMUT00000046354.3
      Conserved Domains (4) summary
      cd00204
      Location:490 → 583
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam04960
      Location:177 → 463
      Glutaminase; Glutaminase
      pfam13637
      Location:520 → 572
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:490 → 516
      ANK; ANK repeat [structural motif]

    2. XM_015152016.2 → XP_015007502.1  glutaminase liver isoform, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A1D5R0A7
      Conserved Domains (4) summary
      cd00204
      Location:434 → 527
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam04960
      Location:121 → 407
      Glutaminase; Glutaminase
      pfam13637
      Location:464 → 516
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:434 → 460
      ANK; ANK repeat [structural motif]

    3. XM_015152015.2 → XP_015007501.1  glutaminase liver isoform, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A1D5R0A7
      Conserved Domains (4) summary
      cd00204
      Location:440 → 533
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam04960
      Location:127 → 413
      Glutaminase; Glutaminase
      pfam13637
      Location:470 → 522
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:440 → 466
      ANK; ANK repeat [structural motif]

    4. XM_028829614.1 → XP_028685447.1  glutaminase liver isoform, mitochondrial isoform X4

      UniProtKB/TrEMBL
      F6TFZ2, F6TG02
      Related
      ENSMMUP00000001154.4, ENSMMUT00000001230.4
      Conserved Domains (3) summary
      sd00045
      Location:225 → 251
      ANK; ANK repeat [structural motif]
      pfam04960
      Location:1 → 196
      Glutaminase
      pfam12796
      Location:225 → 318
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_028829615.1 → XP_028685448.1  glutaminase liver isoform, mitochondrial isoform X4

      UniProtKB/TrEMBL
      F6TFZ2, F6TG02
      Related
      ENSMMUP00000001155.4, ENSMMUT00000001231.4
      Conserved Domains (3) summary
      sd00045
      Location:225 → 251
      ANK; ANK repeat [structural motif]
      pfam04960
      Location:1 → 196
      Glutaminase
      pfam12796
      Location:225 → 318
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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