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    HMOX2 heme oxygenase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705461, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HMOX2provided by VGNC
    Official Full Name
    heme oxygenase 2provided by VGNC
    Primary source
    VGNC:VGNC:73489
    Locus tag
    EGK_12451
    See related
    Ensembl:ENSMMUG00000009901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HMOX2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (4555513..4592742)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (4472613..4516967)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member A3 Neighboring gene NmrA like redox sensor 1 Neighboring gene uncharacterized LOC114674412 Neighboring gene cell death inducing p53 target 1 Neighboring gene chromosome 20 C16orf96 homolog Neighboring gene uncharacterized protein C8orf59 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heme oxygenase (decyclizing) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heme catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heme oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heme oxygenase 2
    Names
    heme oxygenase (decycling) 2
    NP_001252998.1
    XP_014980970.1
    XP_014980971.1
    XP_028696310.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266069.1 → NP_001252998.1  heme oxygenase 2

      See identical proteins and their annotated locations for NP_001252998.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045002
      UniProtKB/TrEMBL
      A0A1D5R7H0, A0A8J8YAB9, F6YK72, G7NPJ0, I0FKU7
      Related
      ENSMMUP00000070371.1, ENSMMUT00000106085.1
      Conserved Domains (2) summary
      cd19165
      Location:147 → 174
      HemeO; kinked helix [structural motif]
      pfam01126
      Location:31 → 236
      Heme_oxygenase; Heme oxygenase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      4555513..4592742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840477.1 → XP_028696310.1  heme oxygenase 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R7H0, A0A8J8YAB9, F6YK72, G7NPJ0, I0FKU7
      Related
      ENSMMUP00000012959.4, ENSMMUT00000013829.4
      Conserved Domains (2) summary
      cd19165
      Location:147 → 174
      HemeO; kinked helix [structural motif]
      pfam01126
      Location:31 → 236
      Heme_oxygenase; Heme oxygenase

    2. XM_015125485.2 → XP_014980971.1  heme oxygenase 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R7H0, A0A8J8YAB9, F6YK72, G7NPJ0, I0FKU7
      Conserved Domains (2) summary
      cd19165
      Location:147 → 174
      HemeO; kinked helix [structural motif]
      pfam01126
      Location:31 → 236
      Heme_oxygenase; Heme oxygenase

    3. XM_015125484.2 → XP_014980970.1  heme oxygenase 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R7H0, A0A8J8YAB9, F6YK72, G7NPJ0, I0FKU7
      Conserved Domains (2) summary
      cd19165
      Location:147 → 174
      HemeO; kinked helix [structural motif]
      pfam01126
      Location:31 → 236
      Heme_oxygenase; Heme oxygenase
    Nucleotide Protein
    Heading Accession and Version

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