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    SH2B3 SH2B adaptor protein 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710839, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SH2B3provided by VGNC
    Official Full Name
    SH2B adaptor protein 3provided by VGNC
    Primary source
    VGNC:VGNC:77340
    See related
    Ensembl:ENSMMUG00000002223
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    LNK
    Orthologs
    human mouse all
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    Genomic context

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    See SH2B3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (111072664..111118703)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (111415315..111460910)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene PH domain containing endocytic trafficking adaptor 1 Neighboring gene heat shock cognate 71 kDa protein pseudogene Neighboring gene ataxin 2 Neighboring gene U7 small nuclear RNA Neighboring gene interferon-induced transmembrane protein 3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH2B adapter protein 3
    Names
    lymphocyte adaptor protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      111072664..111118703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028829901.1 → XP_028685734.1  SH2B adapter protein 3 isoform X5

      Conserved Domains (4) summary
      PRK13881
      Location:90 → 236
      PRK13881; conjugal transfer protein TrbI; Provisional
      cd01231
      Location:194 → 312
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:25 → 80
      Phe_ZIP; Phenylalanine zipper
      cl15255
      Location:359 → 487
      SH2; Src homology 2 (SH2) domain

    2. XM_001108790.4 → XP_001108790.1  SH2B adapter protein 3 isoform X6

      UniProtKB/TrEMBL
      F6W719
      Related
      ENSMMUP00000002972.1, ENSMMUT00000003148.3
      Conserved Domains (4) summary
      cd10412
      Location:358 → 454
      SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
      cd01231
      Location:194 → 312
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam00169
      Location:237 → 308
      PH; PH domain
      pfam08916
      Location:25 → 80
      Phe_ZIP; Phenylalanine zipper

    3. XM_028829898.1 → XP_028685731.1  SH2B adapter protein 3 isoform X1

      Conserved Domains (4) summary
      PRK13881
      Location:180 → 326
      PRK13881; conjugal transfer protein TrbI; Provisional
      cd01231
      Location:284 → 402
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:115 → 170
      Phe_ZIP; Phenylalanine zipper
      cl15255
      Location:449 → 577
      SH2; Src homology 2 (SH2) domain

    4. XM_015152815.2 → XP_015008301.1  SH2B adapter protein 3 isoform X3

      Conserved Domains (4) summary
      cd10412
      Location:449 → 545
      SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
      cd01231
      Location:284 → 402
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam00169
      Location:327 → 398
      PH; PH domain
      pfam08916
      Location:115 → 170
      Phe_ZIP; Phenylalanine zipper

    5. XM_028829899.1 → XP_028685732.1  SH2B adapter protein 3 isoform X2

      Conserved Domains (4) summary
      PRK13881
      Location:180 → 326
      PRK13881; conjugal transfer protein TrbI; Provisional
      cd01231
      Location:284 → 402
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam08916
      Location:115 → 170
      Phe_ZIP; Phenylalanine zipper
      cl15255
      Location:448 → 576
      SH2; Src homology 2 (SH2) domain

    6. XM_015152816.2 → XP_015008302.1  SH2B adapter protein 3 isoform X4

      Conserved Domains (4) summary
      cd10412
      Location:448 → 544
      SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
      cd01231
      Location:284 → 402
      PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
      pfam00169
      Location:327 → 398
      PH; PH domain
      pfam08916
      Location:115 → 170
      Phe_ZIP; Phenylalanine zipper

    7. XM_015152818.2 → XP_015008304.1  SH2B adapter protein 3 isoform X7

      UniProtKB/TrEMBL
      G7N5H7
      Conserved Domains (2) summary
      cd10412
      Location:153 → 249
      SH2_SH2B3; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
      cl17171
      Location:13 → 107
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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