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    PLCL1 phospholipase C like 1 (inactive) [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698200, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLCL1provided by VGNC
    Official Full Name
    phospholipase C like 1 (inactive)provided by VGNC
    Primary source
    VGNC:VGNC:99393
    See related
    Ensembl:ENSMMUG00000012822
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLCL1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (84893825..85253467)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (148257602..148609131, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene methionyl-tRNA synthetase 2, mitochondrial Neighboring gene uncharacterized LOC106997074 Neighboring gene boule homolog, RNA binding protein Neighboring gene uncharacterized LOC106997073 Neighboring gene uncharacterized LOC114671385 Neighboring gene uncharacterized LOC114671386 Neighboring gene uncharacterized LOC106997072

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inactive phospholipase C-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260854.1 → NP_001247783.1  inactive phospholipase C-like protein 1

      See identical proteins and their annotated locations for NP_001247783.1

      Status: PROVISIONAL

      Source sequence(s)
      JU476025
      UniProtKB/TrEMBL
      A0A5F8AFD6, H9ERR5
      Related
      ENSMMUP00000049524.1, ENSMMUT00000076307.2
      Conserved Domains (6) summary
      cd00275
      Location:720 → 848
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08597
      Location:398 → 688
      PI-PLCc_PRIP_metazoa; Catalytic domain of metazoan phospholipase C related, but catalytically inactive protein
      PLN02228
      Location:330 → 850
      PLN02228; Phosphoinositide phospholipase C
      cd13364
      Location:115 → 223
      PH_PLC_eta; Phospholipase C-eta (PLC-eta) pleckstrin homology (PH) domain
      pfam00169
      Location:118 → 223
      PH; PH domain
      pfam09279
      Location:315 → 396
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      84893825..85253467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830422.1 → XP_028686255.1  inactive phospholipase C-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZMA7
      Related
      ENSMMUP00000066762.1, ENSMMUT00000104669.1
      Conserved Domains (5) summary
      cd00275
      Location:662 → 790
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08597
      Location:340 → 630
      PI-PLCc_PRIP_metazoa; Catalytic domain of metazoan phospholipase C related, but catalytically inactive protein
      cd13364
      Location:57 → 165
      PH_PLC_eta; Phospholipase C-eta (PLC-eta) pleckstrin homology (PH) domain
      cd15898
      Location:185 → 214
      EFh_PI-PLC; EF-hand motif [structural motif]
      cl28895
      Location:185 → 327
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    Nucleotide Protein
    Heading Accession and Version

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