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    ALOX12B arachidonate 12-lipoxygenase, 12R type [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 721936, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ALOX12Bprovided by VGNC
    Official Full Name
    arachidonate 12-lipoxygenase, 12R typeprovided by VGNC
    Primary source
    VGNC:VGNC:99114
    See related
    Ensembl:ENSMMUG00000020329
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ALOX12B in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (7873058..7887851, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (8089625..8104531, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673050 Neighboring gene small nucleolar RNA U13 Neighboring gene arachidonate 15-lipoxygenase type B Neighboring gene uncharacterized LOC114673051 Neighboring gene arachidonate lipoxygenase 3 Neighboring gene transfer RNA lysine (anticodon UUU)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables arachidonate 12(S)-lipoxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in linoleic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arachidonate 12-lipoxygenase, 12R-type

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      7873058..7887851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015118613.2 → XP_014974099.1  arachidonate 12-lipoxygenase, 12R-type

      UniProtKB/TrEMBL
      F6WGW5, G7NII2
      Related
      ENSMMUP00000026754.3, ENSMMUT00000028594.4
      Conserved Domains (2) summary
      cd01753
      Location:2 → 116
      PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
      pfam00305
      Location:258 → 681
      Lipoxygenase; Lipoxygenase
    Nucleotide Protein
    Heading Accession and Version

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