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    SHC4 SHC adaptor protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714611, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SHC4provided by VGNC
    Official Full Name
    SHC adaptor protein 4provided by VGNC
    Primary source
    VGNC:VGNC:77249
    Locus tag
    EGK_17474
    See related
    Ensembl:ENSMMUG00000009833
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SHC4 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (25239899..25381690, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (25143190..25284845, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999174 Neighboring gene fibrillin 1 Neighboring gene centrosomal protein 152 Neighboring gene EP300 interacting inhibitor of differentiation 1 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene SECIS binding protein 2 like Neighboring gene uncharacterized LOC114679398

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SHC-transforming protein 4
    Names
    SHC (Src homology 2 domain containing) family, member 4
    Src-like proteiny 2 domain-containing-transforming protein C4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      25239899..25381690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001113330.4 → XP_001113330.1  SHC-transforming protein 4

      See identical proteins and their annotated locations for XP_001113330.1

      UniProtKB/TrEMBL
      A0A1D5R2Z0, A0A8J8XQ49, F7A7H5, G7MX95
      Related
      ENSMMUP00000054675.2, ENSMMUT00000072245.2
      Conserved Domains (2) summary
      cd09925
      Location:518 → 618
      SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
      cd01209
      Location:176 → 347
      PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials