PXK PX domain containing serine/threonine kinase like [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PXKprovided by VGNC
Official Full Name: PX domain containing serine/threonine kinase likeprovided by VGNC
Primary source: VGNC:VGNC:76522
See related: Ensembl:ENSMMUG00000006432
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (114491462..114590226)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (83696518..83796355, complement)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

1178 (e-PCR)
- UniSTS:55478

D20S856 (e-PCR), detects polymorphism
- UniSTS:32210

SHGC-80069 (e-PCR)
- UniSTS:102127

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in early endosome to late endosome transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endosome to lysosome transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein targeting to lysosome	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in early endosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in extrinsic component of endosome membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in late endosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: PX domain-containing protein kinase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041755.1 Reference Mmul_10 Primary Assembly

Range

114491462..114590226

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028844294.1 → XP_028700127.1 PX domain-containing protein kinase-like protein isoform X9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130607.2 → XP_014986093.1 PX domain-containing protein kinase-like protein isoform X2

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130609.2 → XP_014986095.1 PX domain-containing protein kinase-like protein isoform X4

UniProtKB/TrEMBL

A0A1D5RIC4, F7H2D9

Related

ENSMMUP00000060068.1, ENSMMUT00000071734.2

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_028844290.1 → XP_028700123.1 PX domain-containing protein kinase-like protein isoform X5

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130610.2 → XP_014986096.1 PX domain-containing protein kinase-like protein isoform X5

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_028844291.1 → XP_028700124.1 PX domain-containing protein kinase-like protein isoform X6

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130611.2 → XP_014986097.1 PX domain-containing protein kinase-like protein isoform X6

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130606.2 → XP_014986092.1 PX domain-containing protein kinase-like protein isoform X1

UniProtKB/TrEMBL

F7H2D9, H9ET08

Related

ENSMMUP00000048328.1, ENSMMUT00000069355.2

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_028844292.1 → XP_028700125.1 PX domain-containing protein kinase-like protein isoform X7

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130613.2 → XP_014986099.1 PX domain-containing protein kinase-like protein isoform X7

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_028844293.1 → XP_028700126.1 PX domain-containing protein kinase-like protein isoform X8

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130614.2 → XP_014986100.1 PX domain-containing protein kinase-like protein isoform X8

UniProtKB/TrEMBL

F7H2D9

Conserved Domains (2) summary

cd06871
Location:13 → 132

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:198 → 345

PKc; Catalytic domain of Protein Kinases
XM_015130608.2 → XP_014986094.1 PX domain-containing protein kinase-like protein isoform X3

UniProtKB/TrEMBL

G8F1P9

Conserved Domains (2) summary

cd06871
Location:26 → 123

PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase

cd00180
Location:189 → 336

PKc; Catalytic domain of Protein Kinases
XM_028844295.1 → XP_028700128.1 PX domain-containing protein kinase-like protein isoform X10

UniProtKB/TrEMBL

G8F1P9

Conserved Domains (2) summary

cd00180
Location:115 → 262

PKc; Catalytic domain of Protein Kinases

cl02563
Location:1 → 49

PX_domain; The Phox Homology domain, a phosphoinositide binding module