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    IQGAP3 IQ motif containing GTPase activating protein 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719575, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IQGAP3provided by VGNC
    Official Full Name
    IQ motif containing GTPase activating protein 3provided by VGNC
    Primary source
    VGNC:VGNC:73634
    See related
    Ensembl:ENSMMUG00000002621
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IQGAP3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (94394603..94439654)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (131146873..131199319, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene NAD(P)HX epimerase Neighboring gene tetratricopeptide repeat domain 24 Neighboring gene small nucleolar RNA U13 Neighboring gene myocyte enhancer factor 2D Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC106992900

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras GTPase-activating-like protein IQGAP3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      94394603..94439654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114017.4 → XP_001114017.3  ras GTPase-activating-like protein IQGAP3 isoform X1

      UniProtKB/TrEMBL
      G7ME01
      Conserved Domains (3) summary
      cd12207
      Location:988 → 1337
      RasGAP_IQGAP3; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 3
      COG5022
      Location:735 → 958
      COG5022; Myosin heavy chain [General function prediction only]
      COG5261
      Location:862 → 1632
      IQG1; Protein involved in regulation of cellular morphogenesis/cytokinesis [Cell division and chromosome partitioning / Signal transduction mechanisms]

    2. XM_015112166.2 → XP_014967652.2  ras GTPase-activating-like protein IQGAP3 isoform X2

      UniProtKB/TrEMBL
      F7H7C9, G7ME01
      Related
      ENSMMUP00000003526.4, ENSMMUT00000003732.4
      Conserved Domains (3) summary
      cd12207
      Location:987 → 1336
      RasGAP_IQGAP3; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 3
      COG5022
      Location:734 → 957
      COG5022; Myosin heavy chain [General function prediction only]
      COG5261
      Location:861 → 1631
      IQG1; Protein involved in regulation of cellular morphogenesis/cytokinesis [Cell division and chromosome partitioning / Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials