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    LAMB4 laminin subunit beta 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702225, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LAMB4provided by VGNC
    Official Full Name
    laminin subunit beta 4provided by VGNC
    Primary source
    VGNC:VGNC:74231
    See related
    Ensembl:ENSMMUG00000021289
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See LAMB4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (134344345..134453491, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (133444963..133554061, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677010 Neighboring gene laminin subunit beta 1 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC114677011 Neighboring gene neuronal cell adhesion molecule Neighboring gene U7 small nuclear RNA Neighboring gene patatin like phospholipase domain containing 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in basement membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of laminin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit beta-4
    Names
    laminin, beta 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      134344345..134453491 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846172.1 → XP_028702005.1  laminin subunit beta-4 isoform X3

      UniProtKB/TrEMBL
      G7MM44
      Conserved Domains (4) summary
      cd00055
      Location:454 → 503
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      TIGR04523
      Location:1249 → 1691
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam00053
      Location:1080 → 1128
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:40 → 263
      Laminin_N; Laminin N-terminal (Domain VI)

    2. XM_028846170.1 → XP_028702003.1  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QZD8, F6V7L7, G7MM44
      Related
      ENSMMUP00000053420.2, ENSMMUT00000053728.2
      Conserved Domains (4) summary
      cd00055
      Location:454 → 503
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      TIGR04523
      Location:1414 → 1755
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam00053
      Location:1080 → 1128
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:40 → 263
      Laminin_N; Laminin N-terminal (Domain VI)

    3. XM_015134674.2 → XP_014990160.2  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QZD8, F6V7L7, G7MM44
      Conserved Domains (4) summary
      cd00055
      Location:454 → 503
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      TIGR04523
      Location:1414 → 1755
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam00053
      Location:1080 → 1128
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:40 → 263
      Laminin_N; Laminin N-terminal (Domain VI)

    4. XM_028846171.1 → XP_028702004.1  laminin subunit beta-4 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AQL6, G7MM44
      Related
      ENSMMUP00000080240.1, ENSMMUT00000085537.1
      Conserved Domains (4) summary
      COG0419
      Location:1214 → 1720
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00055
      Location:454 → 503
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      pfam00053
      Location:1080 → 1128
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:40 → 263
      Laminin_N; Laminin N-terminal (Domain VI)

    5. XM_028846173.1 → XP_028702006.1  laminin subunit beta-4 isoform X4

      Conserved Domains (3) summary
      cd00055
      Location:454 → 503
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      pfam00053
      Location:395 → 452
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:40 → 263
      Laminin_N; Laminin N-terminal (Domain VI)
    Nucleotide Protein
    Heading Accession and Version

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