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    BRAP BRCA1 associated protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713386, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BRAPprovided by VGNC
    Official Full Name
    BRCA1 associated proteinprovided by VGNC
    Primary source
    VGNC:VGNC:70278
    Locus tag
    EGK_04195
    See related
    Ensembl:ENSMMUG00000017107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See BRAP in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (111313093..111357183, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (111659310..111704339, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene ataxin 2 Neighboring gene U7 small nuclear RNA Neighboring gene interferon-induced transmembrane protein 3 pseudogene Neighboring gene 40S ribosomal protein S18 pseudogene Neighboring gene acyl-CoA dehydrogenase family member 10 Neighboring gene aldehyde dehydrogenase 2 family member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BRCA1-associated protein
    NP_001252865.1
    XP_015008285.1
    XP_028684809.1
    XP_028684810.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265936.1 → NP_001252865.1  BRCA1-associated protein

      See identical proteins and their annotated locations for NP_001252865.1

      Status: PROVISIONAL

      Source sequence(s)
      JU477411
      UniProtKB/TrEMBL
      A0A5F8AS18, A0A8J8XZE1, F7H5B0, G7N5H9
      Related
      ENSMMUP00000079867.1, ENSMMUT00000108455.1
      Conserved Domains (4) summary
      cd00162
      Location:263 → 304
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd12718
      Location:160 → 243
      RRM_BRAP2; RNA recognition motif in BRCA1-associated protein (BRAP2)
      pfam02148
      Location:317 → 379
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl23887
      Location:407 → 558
      DUF4349; Domain of unknown function (DUF4349)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      111313093..111357183 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828976.1 → XP_028684809.1  BRCA1-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A5F8A555, F7H5B0
      Related
      ENSMMUP00000073074.1, ENSMMUT00000082602.1
      Conserved Domains (4) summary
      COG1196
      Location:359 → 527
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd16457
      Location:224 → 267
      RING-H2_BRAP2; RING finger, H2 subclass, found in BRCA1-associated protein (BRAP2) and similar proteins
      pfam02148
      Location:279 → 341
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl17169
      Location:160 → 211
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_028828977.1 → XP_028684810.1  BRCA1-associated protein isoform X3

      UniProtKB/TrEMBL
      F7H5B0
      Conserved Domains (3) summary
      TIGR02168
      Location:332 → 474
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd16457
      Location:262 → 305
      RING-H2_BRAP2; RING finger, H2 subclass, found in BRCA1-associated protein (BRAP2) and similar proteins
      cd12718
      Location:160 → 243
      RRM_BRAP2; RNA recognition motif (RRM) found in BRCA1-associated protein (BRAP2)

    3. XM_015152799.2 → XP_015008285.1  BRCA1-associated protein isoform X1

      UniProtKB/TrEMBL
      F7H5B0
      Related
      ENSMMUP00000075440.1, ENSMMUT00000105029.1
      Conserved Domains (4) summary
      cd00162
      Location:233 → 274
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd12718
      Location:130 → 213
      RRM_BRAP2; RNA recognition motif in BRCA1-associated protein (BRAP2)
      pfam02148
      Location:287 → 349
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl23887
      Location:377 → 528
      DUF4349; Domain of unknown function (DUF4349)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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