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    LRRC8A leucine rich repeat containing 8 VRAC subunit A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717074, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LRRC8Aprovided by VGNC
    Official Full Name
    leucine rich repeat containing 8 VRAC subunit Aprovided by VGNC
    Primary source
    VGNC:VGNC:81438
    See related
    Ensembl:ENSMMUG00000017799
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LRRC8A in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (11643354..11682735, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (9926389..9965961, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene dolichol kinase Neighboring gene phytanoyl-CoA dioxygenase domain containing 1 Neighboring gene kynurenine aminotransferase 1 Neighboring gene SPOUT domain containing methyltransferase 1 Neighboring gene endonuclease G

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    volume-regulated anion channel subunit LRRC8A
    Names
    leucine rich repeat containing 8 family member A
    leucine-rich repeat-containing protein 8A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257576.1 → NP_001244505.1  volume-regulated anion channel subunit LRRC8A

      See identical proteins and their annotated locations for NP_001244505.1

      Status: PROVISIONAL

      Source sequence(s)
      JU335482
      UniProtKB/TrEMBL
      F7E1A8, G7NFR1
      Related
      ENSMMUP00000023403.2, ENSMMUT00000025013.4
      Conserved Domains (4) summary
      COG4886
      Location:568 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      NF033189
      Location:379 → 713
      internalin_A; class 1 internalin InlA
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      11643354..11682735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834399.1 → XP_028690232.1  volume-regulated anion channel subunit LRRC8A isoform X1

      UniProtKB/TrEMBL
      F7E1A8, G7NFR1
      Conserved Domains (4) summary
      COG4886
      Location:568 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      NF033189
      Location:379 → 713
      internalin_A; class 1 internalin InlA
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials