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    IL6R interleukin 6 receptor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716690, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IL6Rprovided by VGNC
    Official Full Name
    interleukin 6 receptorprovided by VGNC
    Primary source
    VGNC:VGNC:73733
    See related
    Ensembl:ENSMMUG00000022978
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IL6R in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (96570516..96633105, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (129037531..129100252)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 Q1 Neighboring gene tudor domain containing 10 Neighboring gene Src homology 2 domain containing E Neighboring gene 26S proteasome non-ATPase regulatory subunit 8 pseudogene Neighboring gene U7 small nuclear RNA Neighboring gene ATPase phospholipid transporting 8B2 Neighboring gene aquaporin 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables interleukin-11 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables interleukin-11 receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables interleukin-6 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interleukin-6-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-6 receptor subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      96570516..96633105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114404.4 → XP_001114404.2  interleukin-6 receptor subunit alpha isoform X2

      Conserved Domains (3) summary
      smart00408
      Location:268 → 326
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:445 → 537
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:347 → 442
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    2. XM_028828596.1 → XP_028684429.1  interleukin-6 receptor subunit alpha isoform X1

      Conserved Domains (3) summary
      smart00408
      Location:268 → 326
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:445 → 537
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:347 → 442
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    3. XM_028828609.1 → XP_028684442.1  interleukin-6 receptor subunit alpha isoform X3

      Conserved Domains (3) summary
      smart00408
      Location:268 → 326
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:445 → 537
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:347 → 442
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    RNA

    1. XR_003720212.1 RNA Sequence

      Related
      ENSMMUT00000032343.4
    Nucleotide Protein
    Heading Accession and Version

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