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    TRAF5 TNF receptor associated factor 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711879, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TRAF5provided by VGNC
    Official Full Name
    TNF receptor associated factor 5provided by VGNC
    Primary source
    VGNC:VGNC:78644
    See related
    Ensembl:ENSMMUG00000031427
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TRAF5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (68814132..68861313)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (155153509..155202674, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene REST corepressor 3 Neighboring gene putative uncharacterized protein encoded by LINC00467 homolog Neighboring gene actin-related protein 2/3 complex subunit 3 pseudogene Neighboring gene RD3 regulator of GUCY2D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thioesterase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of plasma membrane signaling receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TNF receptor-associated factor 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      68814132..68861313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117425.2 → XP_014972911.1  TNF receptor-associated factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AI01, H9ZD17
      Conserved Domains (5) summary
      COG1196
      Location:233 → 398
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02176
      Location:183 → 241
      zf-TRAF; TRAF-type zinc finger
      cd16642
      Location:43 → 85
      mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins
      cl02446
      Location:404 → 550
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl40617
      Location:128 → 183
      zf-TRAF; TRAF-type zinc finger

    2. XM_015117407.2 → XP_014972893.1  TNF receptor-associated factor 5 isoform X1

      UniProtKB/TrEMBL
      H9ZD17
      Conserved Domains (3) summary
      smart00184
      Location:60 → 96
      RING; Ring finger
      pfam02176
      Location:198 → 256
      zf-TRAF; TRAF-type zinc finger
      cl02446
      Location:419 → 565
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

    3. XM_028852879.1 → XP_028708712.1  TNF receptor-associated factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AI01, H9ZD17
      Related
      ENSMMUP00000065408.1, ENSMMUT00000087102.1
      Conserved Domains (5) summary
      COG1196
      Location:233 → 398
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02176
      Location:183 → 241
      zf-TRAF; TRAF-type zinc finger
      cd16642
      Location:43 → 85
      mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins
      cl02446
      Location:404 → 550
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl40617
      Location:128 → 183
      zf-TRAF; TRAF-type zinc finger

    4. XM_028852877.1 → XP_028708710.1  TNF receptor-associated factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AI01, H9ZD17
      Conserved Domains (5) summary
      COG1196
      Location:233 → 398
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02176
      Location:183 → 241
      zf-TRAF; TRAF-type zinc finger
      cd16642
      Location:43 → 85
      mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins
      cl02446
      Location:404 → 550
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl40617
      Location:128 → 183
      zf-TRAF; TRAF-type zinc finger

    5. XM_015117415.2 → XP_014972901.1  TNF receptor-associated factor 5 isoform X2

      UniProtKB/TrEMBL
      F7FNK1, H9ZD17
      Related
      ENSMMUP00000038268.2, ENSMMUT00000045246.3
      Conserved Domains (3) summary
      smart00184
      Location:57 → 93
      RING; Ring finger
      pfam02176
      Location:195 → 253
      zf-TRAF; TRAF-type zinc finger
      cl02446
      Location:416 → 562
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    Nucleotide Protein
    Heading Accession and Version

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