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    RPTOR regulatory associated protein of MTOR complex 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712848, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RPTORprovided by VGNC
    Official Full Name
    regulatory associated protein of MTOR complex 1provided by VGNC
    Primary source
    VGNC:VGNC:99224
    See related
    Ensembl:ENSMMUG00000006761
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RPTOR in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (76882261..77302938)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (74405410..74829057)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene neuronal pentraxin 1 Neighboring gene uncharacterized LOC114673021 Neighboring gene uncharacterized LOC114673205 Neighboring gene uncharacterized LOC106994153 Neighboring gene charged multivesicular body protein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to amino acid stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TORC1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulatory-associated protein of mTOR

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      76882261..77302938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120520.2 → XP_014976006.1  regulatory-associated protein of mTOR isoform X1

      UniProtKB/TrEMBL
      F6QEI3, F7HCZ9, H9EN45
      Related
      ENSMMUP00000008896.3, ENSMMUT00000009463.4
      Conserved Domains (5) summary
      sd00044
      Location:516 → 544
      HEAT; HEAT repeat [structural motif]
      sd00039
      Location:1027 → 1063
      7WD40; WD40 repeat [structural motif]
      pfam14538
      Location:60 → 206
      Raptor_N; Raptor N-terminal CASPase like domain
      cl25539
      Location:1027 → 1322
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl26317
      Location:472 → 696
      Adaptin_N; Adaptin N terminal region

    2. XM_015120521.2 → XP_014976007.1  regulatory-associated protein of mTOR isoform X2

      UniProtKB/TrEMBL
      F6QEI3
      Conserved Domains (6) summary
      COG5096
      Location:418 → 642
      COG5096; Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]
      sd00044
      Location:462 → 490
      HEAT; HEAT repeat [structural motif]
      sd00039
      Location:973 → 1009
      7WD40; WD40 repeat [structural motif]
      pfam13646
      Location:512 → 614
      HEAT_2; HEAT repeats
      pfam14538
      Location:1 → 152
      Raptor_N; Raptor N-terminal CASPase like domain
      cl29593
      Location:973 → 1268
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_028836899.1 → XP_028692732.1  regulatory-associated protein of mTOR isoform X2

      UniProtKB/TrEMBL
      F6QEI3
      Conserved Domains (6) summary
      COG5096
      Location:418 → 642
      COG5096; Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]
      sd00044
      Location:462 → 490
      HEAT; HEAT repeat [structural motif]
      sd00039
      Location:973 → 1009
      7WD40; WD40 repeat [structural motif]
      pfam13646
      Location:512 → 614
      HEAT_2; HEAT repeats
      pfam14538
      Location:1 → 152
      Raptor_N; Raptor N-terminal CASPase like domain
      cl29593
      Location:973 → 1268
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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