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    BRD4 bromodomain containing 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718195, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BRD4provided by VGNC
    Official Full Name
    bromodomain containing 4provided by VGNC
    Primary source
    VGNC:VGNC:70301
    See related
    Ensembl:ENSMMUG00000021382
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See BRD4 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (14839684..14936896, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (15138462..15183913, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene notch receptor 3 Neighboring gene epoxide hydrolase 3 Neighboring gene uncharacterized LOC106994653 Neighboring gene A-kinase anchoring protein 8 Neighboring gene A-kinase anchoring protein 8 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lysine-acetylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bromodomain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      14839684..14936896 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028839348.1 → XP_028695181.1  bromodomain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      F7FHI3
      Related
      ENSMMUP00000072441.1, ENSMMUT00000106787.1
      Conserved Domains (4) summary
      cd05497
      Location:58 → 164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:353 → 454
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:608 → 672
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:1320 → 1363
      BRD4_CDT; C-terminal domain of bromodomain protein 4

    2. XM_028839349.1 → XP_028695182.1  bromodomain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      F7FDM7, H9Z730
      Related
      ENSMMUP00000028170.4, ENSMMUT00000030100.4
      Conserved Domains (3) summary
      cd05497
      Location:58 → 164
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:353 → 454
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:608 → 672
      BET; Bromodomain extra-terminal - transcription regulation
    Nucleotide Protein
    Heading Accession and Version

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