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    APBA2 amyloid beta precursor protein binding family A member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712426, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APBA2provided by VGNC
    Official Full Name
    amyloid beta precursor protein binding family A member 2provided by VGNC
    Primary source
    VGNC:VGNC:69977
    See related
    Ensembl:ENSMMUG00000019339
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See APBA2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (8390913..8627496, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (5494646..5733928)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene DDB1- and CUL4-associated factor 6 pseudogene Neighboring gene NSE3 homolog, SMC5-SMC6 complex component Neighboring gene uncharacterized LOC114679353 Neighboring gene proline-rich receptor-like protein kinase PERK10 Neighboring gene golgin subfamily A member 6-like protein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amyloid-beta A4 precursor protein-binding family A member 2
    Names
    amyloid beta A4 precursor protein-binding family A member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      8390913..8627496 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028850682.1 → XP_028706515.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QT06, F6PW11, H9EUQ7
      Related
      ENSMMUP00000070611.1, ENSMMUT00000096956.1
      Conserved Domains (3) summary
      cd00992
      Location:657 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 535
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:568 → 651
      PDZ; PDZ domain (Also known as DHR or GLGF)

    2. XM_028850681.1 → XP_028706514.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QT06, F6PW11, H9EUQ7
      Conserved Domains (3) summary
      cd00992
      Location:657 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 535
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:568 → 651
      PDZ; PDZ domain (Also known as DHR or GLGF)

    3. XM_015141737.2 → XP_014997223.2  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QT06, F6PW11, H9EUQ7
      Related
      ENSMMUP00000051185.2, ENSMMUT00000053429.2
      Conserved Domains (3) summary
      cd00992
      Location:657 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 535
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:568 → 651
      PDZ; PDZ domain (Also known as DHR or GLGF)

    4. XM_015141738.2 → XP_014997224.2  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QT06, F6PW11, H9EUQ7
      Conserved Domains (3) summary
      cd00992
      Location:657 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 535
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:568 → 651
      PDZ; PDZ domain (Also known as DHR or GLGF)

    5. XM_015141739.2 → XP_014997225.2  amyloid-beta A4 precursor protein-binding family A member 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QRK9, F6PW11, H9EUS2
      Related
      ENSMMUP00000050687.2, ENSMMUT00000077819.2
      Conserved Domains (4) summary
      cd00992
      Location:645 → 718
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 523
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam15479
      Location:188 → 360
      DUF4639; Domain of unknown function (DUF4639)
      pfam00595
      Location:556 → 639
      PDZ; PDZ domain (Also known as DHR or GLGF)

    6. XM_028850683.1 → XP_028706516.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QT06, F6PW11, H9EUQ7
      Conserved Domains (3) summary
      cd00992
      Location:657 → 730
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01208
      Location:363 → 535
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:568 → 651
      PDZ; PDZ domain (Also known as DHR or GLGF)

    7. XM_028850684.1 → XP_028706517.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A4U0
      Related
      ENSMMUP00000072381.1, ENSMMUT00000080015.1
      Conserved Domains (2) summary
      PRK07764
      Location:501 → 687
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01208
      Location:363 → 506
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain

    8. XM_015141740.2 → XP_014997226.2  amyloid-beta A4 precursor protein-binding family A member 2 isoform X3

      Conserved Domains (2) summary
      PRK07764
      Location:513 → 699
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01208
      Location:363 → 518
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
    Nucleotide Protein
    Heading Accession and Version

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