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    SH3BP1 SH3 domain binding protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700647, updated on 1-Aug-2024

    Summary

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    Gene symbol
    SH3BP1
    Gene description
    SH3 domain binding protein 1
    See related
    Ensembl:ENSMMUG00000003854
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SH3BP1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (13891259..13919414, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (79627051..79642914)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene TRIO and F-actin binding protein Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like Neighboring gene nucleolar protein 12 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 1 Neighboring gene galectin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rac protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH3 domain-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      13891259..13919414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827737.1 → XP_028683570.1  SH3 domain-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      F6QUV4
      Related
      ENSMMUP00000037019.2, ENSMMUT00000044015.3
      Conserved Domains (3) summary
      cd07620
      Location:16 → 272
      BAR_SH3BP1; The Bin/Amphiphysin/Rvs (BAR) domain of SH3-domain Binding Protein 1
      TIGR01452
      Location:564 → 661
      PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
      cl02570
      Location:272 → 473
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    2. XM_015150293.2 → XP_015005779.1  SH3 domain-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      F6YG46
      Related
      ENSMMUP00000000486.4, ENSMMUT00000000529.4
      Conserved Domains (3) summary
      TIGR01452
      Location:18 → 294
      PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
      pfam13242
      Location:214 → 294
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:22 → 128
      Hydrolase_6; Haloacid dehalogenase-like hydrolase

    3. XM_015150292.2 → XP_015005778.1  SH3 domain-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      F7HAB0
      Related
      ENSMMUP00000005139.4, ENSMMUT00000005460.4
      Conserved Domains (2) summary
      cl02570
      Location:272 → 473
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
      cl12013
      Location:16 → 272
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_028827736.1 → XP_028683569.1  SH3 domain-binding protein 1 isoform X2

      Conserved Domains (2) summary
      cl02570
      Location:208 → 409
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl12013
      Location:1 → 208
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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