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    CYP17A1 cytochrome P450 family 17 subfamily A member 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 678693, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CYP17A1provided by VGNC
    Official Full Name
    cytochrome P450 family 17 subfamily A member 1provided by VGNC
    Primary source
    VGNC:VGNC:103620
    See related
    Ensembl:ENSMMUG00000017601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CYP17
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See CYP17A1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (103372364..103379292, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (98571170..98578099, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene sideroflexin 2 Neighboring gene WW domain binding protein 1 like Neighboring gene uncharacterized LOC114670029 Neighboring gene U6 spliceosomal RNA Neighboring gene BLOC-1 related complex subunit 7 Neighboring gene arsenite methyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of marmoset P450c17 cDNA and gene regulation in vitro. Pattison JC, et al. Endocr Res, 2004 Nov. PMID 15666819
    2. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. Arlt W, et al. Endocrinology, 2002 Dec. PMID 12446594
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid 17-alpha-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hormone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in progesterone metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    steroid 17-alpha-hydroxylase/17,20 lyase
    Names
    17-alpha-hydroxyprogesterone aldolase
    CYPXVII
    cytochrome P450 17 alpha-hydroxylase
    cytochrome P450 17A1
    cytochrome P450 subfamily XVII
    cytochrome P450, family 17, subfamily A, polypeptide 1
    cytochrome P450-C17
    cytochrome P450c17
    steroid 17-alpha-monooxygenase
    NP_001035322.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040232.1 → NP_001035322.1  steroid 17-alpha-hydroxylase/17,20 lyase

      See identical proteins and their annotated locations for NP_001035322.1

      Status: PROVISIONAL

      Source sequence(s)
      AY746983
      UniProtKB/Swiss-Prot
      Q8HYM9
      UniProtKB/TrEMBL
      A0A8J8YM38, F6WI15, G7N114, Q5IFH9
      Related
      ENSMMUP00000023165.2, ENSMMUT00000024752.4
      Conserved Domains (1) summary
      cd20673
      Location:60 → 491
      CYP17A1; cytochrome P450 family 17, subfamily A, polypeptide 1

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      103372364..103379292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8HYM9.1 GenPept UniProtKB/Swiss-Prot:Q8HYM9

    Gene LinkOut

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