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    EXOSC10 exosome component 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714153, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EXOSC10provided by VGNC
    Official Full Name
    exosome component 10provided by VGNC
    Primary source
    VGNC:VGNC:72478
    Locus tag
    EGK_00224
    See related
    Ensembl:ENSMMUG00000019322
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EXOSC10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (213350804..213380719)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (10339283..10369382, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene mechanistic target of rapamycin kinase Neighboring gene angiopoietin like 7 Neighboring gene small nucleolar RNA U13 Neighboring gene spermidine synthase Neighboring gene MBL associated serine protease 2 Neighboring gene TAR DNA binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TRAMP-dependent tRNA surveillance pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in histone mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent CUT catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent antisense transcript catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent rRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent snRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent snoRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in poly(A)-dependent snoRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    exosome component 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      213350804..213380719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001103741.4 → XP_001103741.3  exosome component 10

      UniProtKB/TrEMBL
      F6S2L0
      Related
      ENSMMUP00000025383.3, ENSMMUT00000027134.4
      Conserved Domains (4) summary
      cd06147
      Location:308 → 498
      Rrp6p_like_exo; DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins
      smart00341
      Location:527 → 607
      HRDC; Helicase and RNase D C-terminal
      pfam08505
      Location:216 → 365
      MMR1; Mitochondrial Myo2 receptor-related protein
      pfam08066
      Location:70 → 157
      PMC2NT; PMC2NT (NUC016) domain
    Nucleotide Protein
    Heading Accession and Version

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