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    TRIM45 tripartite motif containing 45 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711397, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TRIM45provided by VGNC
    Official Full Name
    tripartite motif containing 45provided by VGNC
    Primary source
    VGNC:VGNC:79169
    Locus tag
    EGK_01146
    See related
    Ensembl:ENSMMUG00000015976
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM45 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (107141056..107151848)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (118188598..118199426, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene V-set domain containing T cell activation inhibitor 1 Neighboring gene uncharacterized LOC114678105 Neighboring gene uncharacterized LOC114678104 Neighboring gene transcription termination factor 2 Neighboring gene microRNA mir-942 Neighboring gene CD101 molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM45; tripartite motif-containing protein 45
    NP_001253655.1
    XP_015002755.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266726.2 → NP_001253655.1  E3 ubiquitin-protein ligase TRIM45

      See identical proteins and their annotated locations for NP_001253655.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045067
      UniProtKB/TrEMBL
      A0A5S6R941, A0A8J8YDC6, F7HC86, F7HC99, G7MFZ7
      Related
      ENSMMUP00000039315.3, ENSMMUT00000046272.3
      Conserved Domains (4) summary
      smart00557
      Location:399 → 497
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00021
      Location:189 → 226
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      pfam00630
      Location:397 → 494
      Filamin; Filamin/ABP280 repeat
      cl23765
      Location:237 → 357
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      107141056..107151848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147269.2 → XP_015002755.1  tripartite motif-containing protein 45 isoform X1

      UniProtKB/TrEMBL
      F7HC86
      Conserved Domains (4) summary
      smart00557
      Location:342 → 440
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00021
      Location:132 → 169
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      pfam00630
      Location:340 → 437
      Filamin; Filamin/ABP280 repeat
      cl23765
      Location:180 → 300
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    Nucleotide Protein
    Heading Accession and Version

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