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    LOC720399 3-keto-steroid reductase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720399, updated on 19-Jun-2024

    Summary

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    Gene symbol
    LOC720399
    Gene description
    3-keto-steroid reductase
    Locus tag
    EGK_01558
    See related
    Ensembl:ENSMMUG00000009332
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    HSD17B7
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    Genomic context

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    See LOC720399 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (88141563..88159276, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (137592555..137610245)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene 3-keto-steroid reductase-like Neighboring gene discoidin domain receptor tyrosine kinase 2 Neighboring gene UDP-N-acetylglucosamine pyrophosphorylase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-keto sterol reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 5alpha-androstane-3beta,17beta-diol dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-keto-steroid reductase
    Names
    hydroxysteroid 17-beta dehydrogenase 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      88141563..88159276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028826641.1 → XP_028682474.1  3-keto-steroid reductase isoform X2

      UniProtKB/TrEMBL
      A0A5F8AMH4, H9Z9U8
      Related
      ENSMMUP00000078165.1, ENSMMUT00000086537.1
      Conserved Domains (1) summary
      cd08941
      Location:2 → 280
      3KS_SDR_c; 3-keto steroid reductase, classical (c) SDRs

    2. XM_015114093.2 → XP_014969579.1  3-keto-steroid reductase isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q2G2, A0A8J8YNG6, G7MEB9, H9Z9U8
      Related
      ENSMMUP00000042224.1, ENSMMUT00000073771.2
      Conserved Domains (2) summary
      cd08941
      Location:2 → 280
      3KS_SDR_c; 3-keto steroid reductase, classical (c) SDRs
      pfam00106
      Location:3 → 231
      adh_short; short chain dehydrogenase

    3. XM_028826644.1 → XP_028682477.1  3-keto-steroid reductase isoform X3

      Conserved Domains (1) summary
      cl25409
      Location:2 → 110
      SDR; Short-chain dehydrogenases/reductases (SDR)

    4. XM_015114097.2 → XP_014969583.1  3-keto-steroid reductase isoform X3

      Conserved Domains (1) summary
      cl25409
      Location:2 → 110
      SDR; Short-chain dehydrogenases/reductases (SDR)
    Nucleotide Protein
    Heading Accession and Version

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