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    SKIL SKI like proto-oncogene [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696680, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SKILprovided by VGNC
    Official Full Name
    SKI like proto-oncogeneprovided by VGNC
    Primary source
    VGNC:VGNC:84081
    Locus tag
    EGK_11909
    See related
    Ensembl:ENSMMUG00000039099
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SKIL in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (75289093..75326959)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (123398240..123436109, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene polyhomeotic homolog 3 Neighboring gene U7 small nuclear RNA Neighboring gene protein kinase C iota Neighboring gene claudin 11 Neighboring gene solute carrier family 7 member 14 Neighboring gene keratin, type II cytoskeletal 8 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ski-like protein
    Names
    ski-like protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      75289093..75326959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015131630.2 → XP_014987116.1  ski-like protein isoform X2

      UniProtKB/TrEMBL
      A0A5F8AQJ7
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam13863
      Location:538 → 655
      DUF4200; Domain of unknown function (DUF4200)

    2. XM_015131631.2 → XP_014987117.1  ski-like protein isoform X3

      UniProtKB/TrEMBL
      A0A5F8AQJ7
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam17380
      Location:478 → 638
      DUF5401; Family of unknown function (DUF5401)

    3. XM_015131629.2 → XP_014987115.1  ski-like protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q3Q3, A0A5F8AQJ7, A0A8J8XFE5, G7MJB2
      Related
      ENSMMUP00000042665.1, ENSMMUT00000059778.2
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam17380
      Location:524 → 684
      DUF5401; Family of unknown function (DUF5401)

    4. XM_028843849.1 → XP_028699682.1  ski-like protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q3Q3, A0A5F8AQJ7, A0A8J8XFE5, G7MJB2
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam17380
      Location:524 → 684
      DUF5401; Family of unknown function (DUF5401)

    5. XM_028843848.1 → XP_028699681.1  ski-like protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q3Q3, A0A5F8AQJ7, A0A8J8XFE5, G7MJB2
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam17380
      Location:524 → 684
      DUF5401; Family of unknown function (DUF5401)

    6. XM_028843851.1 → XP_028699684.1  ski-like protein isoform X3

      UniProtKB/TrEMBL
      A0A5F8AQJ7
      Conserved Domains (3) summary
      smart01046
      Location:261 → 356
      c-SKI_SMAD_bind; c-SKI Smad4 binding domain
      pfam02437
      Location:136 → 235
      Ski_Sno; SKI/SNO/DAC family
      pfam17380
      Location:478 → 638
      DUF5401; Family of unknown function (DUF5401)
    Nucleotide Protein
    Heading Accession and Version

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