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    NSD3 nuclear receptor binding SET domain protein 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700254, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NSD3provided by VGNC
    Official Full Name
    nuclear receptor binding SET domain protein 3provided by VGNC
    Primary source
    VGNC:VGNC:75398
    See related
    Ensembl:ENSMMUG00000001091
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    WHSC1L1
    Orthologs
    human mouse all
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    Genomic context

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    See NSD3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (38732164..38848300, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (38551336..38664552, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene DDHD domain containing 2 Neighboring gene phospholipid phosphatase 5 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 2 Neighboring gene fibroblast growth factor receptor 1 Neighboring gene skin secretory protein xP2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K36 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase NSD3
    Names
    Wolf-Hirschhorn syndrome candidate 1-like 1
    XP_015000663.2
    XP_015000665.2
    XP_015000666.2
    XP_015000667.2
    XP_015000668.2
    XP_015000669.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      38732164..38848300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015145182.2 → XP_015000668.2  histone-lysine N-methyltransferase NSD3 isoform X5

      UniProtKB/TrEMBL
      F6QLP6, F6QLS4
      Related
      ENSMMUP00000001456.4, ENSMMUT00000001549.4
      Conserved Domains (10) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:910 → 1003
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      smart00570
      Location:1046 → 1096
      AWS; associated with SET domains
      smart00317
      Location:1097 → 1220
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5034
      Location:602 → 746
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15649
      Location:703 → 746
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:751 → 797
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:798 → 850
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:865 → 904
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1275 → 1317
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)

    2. XM_015145180.2 → XP_015000666.2  histone-lysine N-methyltransferase NSD3 isoform X4

      UniProtKB/TrEMBL
      A0A5K1UHM9, F6QLS4
      Related
      ENSMMUP00000029568.4, ENSMMUT00000031606.4
      Conserved Domains (10) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:959 → 1052
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      smart00570
      Location:1095 → 1145
      AWS; associated with SET domains
      smart00317
      Location:1146 → 1269
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5034
      Location:602 → 746
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15649
      Location:703 → 746
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:751 → 797
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:798 → 850
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:918 → 953
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1324 → 1366
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)

    3. XM_015145179.2 → XP_015000665.2  histone-lysine N-methyltransferase NSD3 isoform X2

      UniProtKB/TrEMBL
      F6QLS4
      Conserved Domains (10) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:968 → 1061
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      smart00570
      Location:1104 → 1154
      AWS; associated with SET domains
      smart00317
      Location:1155 → 1267
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5034
      Location:602 → 746
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15649
      Location:703 → 746
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:751 → 797
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:798 → 850
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:929 → 962
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1322 → 1364
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)

    4. XM_015145177.2 → XP_015000663.2  histone-lysine N-methyltransferase NSD3 isoform X1

      UniProtKB/TrEMBL
      F6QLS4
      Conserved Domains (10) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:968 → 1061
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      smart00570
      Location:1104 → 1154
      AWS; associated with SET domains
      smart00317
      Location:1155 → 1278
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5034
      Location:602 → 746
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15649
      Location:703 → 746
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:751 → 797
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:798 → 850
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:929 → 962
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1333 → 1375
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)

    5. XM_015145181.2 → XP_015000667.2  histone-lysine N-methyltransferase NSD3 isoform X3

      UniProtKB/TrEMBL
      F6QLS4
      Related
      ENSMMUP00000001453.4, ENSMMUT00000001546.4
      Conserved Domains (10) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:959 → 1052
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      smart00570
      Location:1095 → 1145
      AWS; associated with SET domains
      smart00317
      Location:1146 → 1258
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5034
      Location:602 → 746
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15649
      Location:703 → 746
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:751 → 797
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:798 → 850
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:918 → 953
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1313 → 1355
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)

    6. XM_015145183.2 → XP_015000669.2  histone-lysine N-methyltransferase NSD3 isoform X6

      UniProtKB/TrEMBL
      F6QLR4
      Related
      ENSMMUP00000001454.3, ENSMMUT00000001547.4
      Conserved Domains (1) summary
      cd05837
      Location:267 → 383
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    Nucleotide Protein
    Heading Accession and Version

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