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    FOXP3 forkhead box P3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574303, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FOXP3provided by VGNC
    Official Full Name
    forkhead box P3provided by VGNC
    Primary source
    VGNC:VGNC:72926
    See related
    Ensembl:ENSMMUG00000008624
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FOXP3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (49238223..49257249, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (49482586..49501407, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene heat shock protein beta-1 pseudogene Neighboring gene coiled-coil domain containing 22 Neighboring gene protein phosphatase 1 regulatory subunit 3F Neighboring gene uncharacterized LOC106995207

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forkhead box protein P3
    Names
    regulatory protein Foxp3
    scurfin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032918.1 → NP_001028090.1  forkhead box protein P3

      See identical proteins and their annotated locations for NP_001028090.1

      Status: PROVISIONAL

      Source sequence(s)
      AY734537
      UniProtKB/TrEMBL
      Q5XW17
      Conserved Domains (2) summary
      cd00059
      Location:337 → 409
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:193 → 260
      FOXP-CC; FOXP coiled-coil domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      49238223..49257249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127312.2 → XP_014982798.1  forkhead box protein P3 isoform X5

      UniProtKB/TrEMBL
      F7CMV8
      Related
      ENSMMUP00000041072.3, ENSMMUT00000048031.3
      Conserved Domains (3) summary
      cd00059
      Location:410 → 482
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam07793
      Location:109 → 219
      DUF1631; Protein of unknown function (DUF1631)
      pfam16159
      Location:266 → 333
      FOXP-CC; FOXP coiled-coil domain

    2. XM_028841639.1 → XP_028697472.1  forkhead box protein P3 isoform X6

      Conserved Domains (3) summary
      PHA03247
      Location:59 → 238
      PHA03247; large tegument protein UL36; Provisional
      pfam16159
      Location:252 → 319
      FOXP-CC; FOXP coiled-coil domain
      pfam00250
      Location:396 → 469
      Forkhead; Forkhead domain

    3. XM_015127309.2 → XP_014982795.1  forkhead box protein P3 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:59 → 252
      PHA03247; large tegument protein UL36; Provisional
      pfam16159
      Location:266 → 333
      FOXP-CC; FOXP coiled-coil domain
      pfam00250
      Location:410 → 543
      Forkhead; Forkhead domain

    4. XM_028841638.1 → XP_028697471.1  forkhead box protein P3 isoform X4

      Conserved Domains (2) summary
      pfam16159
      Location:287 → 354
      FOXP-CC; FOXP coiled-coil domain
      pfam00250
      Location:431 → 504
      Forkhead; Forkhead domain

    5. XM_015127311.2 → XP_014982797.1  forkhead box protein P3 isoform X3

      UniProtKB/TrEMBL
      F7FCX1
      Related
      ENSMMUP00000011310.4, ENSMMUT00000012057.4
      Conserved Domains (2) summary
      cd00059
      Location:445 → 517
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:301 → 368
      FOXP-CC; FOXP coiled-coil domain

    6. XM_015127310.2 → XP_014982796.1  forkhead box protein P3 isoform X2

      Conserved Domains (2) summary
      cd00059
      Location:468 → 540
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:324 → 391
      FOXP-CC; FOXP coiled-coil domain

    7. XM_028841641.1 → XP_028697474.1  forkhead box protein P3 isoform X7

      UniProtKB/TrEMBL
      G7NR98
      Conserved Domains (3) summary
      PHA03247
      Location:2 → 144
      PHA03247; large tegument protein UL36; Provisional
      pfam16159
      Location:158 → 225
      FOXP-CC; FOXP coiled-coil domain
      cd20066
      Location:302 → 442
      FH_FOXP3; Forkhead (FH) domain found in Forkhead box protein P3 (FOXP3) and similar proteins

    8. XM_028841636.1 → XP_028697469.1  forkhead box protein P3 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:59 → 252
      PHA03247; large tegument protein UL36; Provisional
      pfam16159
      Location:266 → 333
      FOXP-CC; FOXP coiled-coil domain
      pfam00250
      Location:410 → 543
      Forkhead; Forkhead domain

    9. XM_028841642.1 → XP_028697475.1  forkhead box protein P3 isoform X7

      UniProtKB/TrEMBL
      G7NR98
      Conserved Domains (3) summary
      PHA03247
      Location:2 → 144
      PHA03247; large tegument protein UL36; Provisional
      pfam16159
      Location:158 → 225
      FOXP-CC; FOXP coiled-coil domain
      cd20066
      Location:302 → 442
      FH_FOXP3; Forkhead (FH) domain found in Forkhead box protein P3 (FOXP3) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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