PVR poliovirus receptor [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: PVR
Gene description: poliovirus receptor
See related: Ensembl:ENSMMUG00000063402
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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Genomic context

Location:: chromosome: 19

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19 Unlocalized Scaffold	NW_021160359.1 (3882..26281)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (39951260..39968572)

NW_021160359.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cell adhesion molecule binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in acrosome assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in coreceptor-mediated virion attachment to host cell	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment of mitochondrion localization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fusion of virus membrane with host plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of immunoglobulin mediated immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of mast cell activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of viral entry into host cell	IEA Inferred from Electronic Annotation more info	PubMed
involved_in susceptibility to T cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in susceptibility to natural killer cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in apical junction complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular exosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in focal adhesion	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: poliovirus receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001043386.1 → NP_001036851.1 poliovirus receptor precursor

See identical proteins and their annotated locations for NP_001036851.1

Status: PROVISIONAL

Source sequence(s)

DQ851092

UniProtKB/TrEMBL

F7DRZ0, Q0MSE6

Related

ENSMMUP00000068430.1, ENSMMUT00000085051.1

Conserved Domains (3) summary

cd07703
Location:145 → 240

Ig2_Nectin-2_like; Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins

smart00410
Location:34 → 141

IG_like; Immunoglobulin like

cl11960
Location:43 → 142

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NW_021160359.1 Reference Mmul_10 Primary Assembly

Range

3882..26281

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028842792.1 → XP_028698625.1 poliovirus receptor isoform X1

UniProtKB/TrEMBL

F7DRZ0

Conserved Domains (3) summary

cd00096
Location:207 → 271

Ig; Immunoglobulin domain

cd07703
Location:90 → 185

Ig2_Nectin-2_like; Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins

cl11960
Location:1 → 87

Ig; Immunoglobulin domain