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    FLNB filamin B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702732, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FLNBprovided by VGNC
    Official Full Name
    filamin Bprovided by VGNC
    Primary source
    VGNC:VGNC:72672
    See related
    Ensembl:ENSMMUG00000000706
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FLNB in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (114150835..114317663)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (83971946..84140505, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene sarcolemma associated protein Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene uncharacterized LOC106996898 Neighboring gene deoxyribonuclease 1L3 Neighboring gene translation machinery-associated protein 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    filamin-B
    Names
    filamin B, beta (actin binding protein 278)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      114150835..114317663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130622.2 → XP_014986108.1  filamin-B isoform X4

      UniProtKB/TrEMBL
      F6YS66, G7ML00
      Related
      ENSMMUP00000000961.4, ENSMMUT00000001024.4
      Conserved Domains (4) summary
      smart00557
      Location:1328 → 1417
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:17 → 121
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00630
      Location:1037 → 1124
      Filamin; Filamin/ABP280 repeat
      cl23780
      Location:1749 → 1804
      PepSY_TM; PepSY-associated TM region

    2. XM_015130621.2 → XP_014986107.1  filamin-B isoform X3

      UniProtKB/TrEMBL
      H9YV08
      Conserved Domains (4) summary
      smart00557
      Location:1421 → 1514
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:17 → 121
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00630
      Location:1418 → 1508
      Filamin; Filamin/ABP280 repeat
      cl23780
      Location:1718 → 1773
      PepSY_TM; PepSY-associated TM region

    3. XM_015130618.2 → XP_014986104.1  filamin-B isoform X1

      UniProtKB/TrEMBL
      H9YV08
      Conserved Domains (4) summary
      smart00557
      Location:1421 → 1514
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:17 → 121
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00630
      Location:1418 → 1508
      Filamin; Filamin/ABP280 repeat
      cl23780
      Location:1718 → 1773
      PepSY_TM; PepSY-associated TM region

    4. XM_015130620.2 → XP_014986106.1  filamin-B isoform X2

      UniProtKB/TrEMBL
      H9YV09
      Related
      ENSMMUP00000070981.1, ENSMMUT00000086320.1
      Conserved Domains (3) summary
      smart00557
      Location:1421 → 1514
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:17 → 121
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00630
      Location:1418 → 1508
      Filamin; Filamin/ABP280 repeat
    Nucleotide Protein
    Heading Accession and Version

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