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    DLG1 discs large MAGUK scaffold protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709572, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DLG1provided by VGNC
    Official Full Name
    discs large MAGUK scaffold protein 1provided by VGNC
    Primary source
    VGNC:VGNC:71918
    See related
    Ensembl:ENSMMUG00000016585
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DLG1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (1801139..2080714, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (203732723..204013834, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein SA pseudogene Neighboring gene uncharacterized LOC106997202 Neighboring gene melanotransferrin Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC106997203

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disks large homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266294.2 → NP_001253223.1  disks large homolog 1

      See identical proteins and their annotated locations for NP_001253223.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045076
      UniProtKB/TrEMBL
      A0A1D5REU1, F6VPG0, H9ENS0
      Related
      ENSMMUP00000058834.2, ENSMMUT00000072947.2
      Conserved Domains (7) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:713 → 891
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      1801139..2080714 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843317.1 → XP_028699150.1  disks large homolog 1 isoform X10

      UniProtKB/TrEMBL
      F7FVU3
      Related
      ENSMMUP00000038227.3, ENSMMUT00000045210.3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:702 → 880
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    2. XM_015132614.2 → XP_014988100.1  disks large homolog 1 isoform X11

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (8) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:712 → 879
      GuKc; Guanylate kinase homologues
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:701 → 879
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    3. XM_015132607.2 → XP_014988093.1  disks large homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A5K1VHC7, F6VPH0, F7FVU9, H9ENR9
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:746 → 913
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:735 → 913
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    4. XM_015132601.2 → XP_014988087.1  disks large homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Related
      ENSMMUP00000021791.4, ENSMMUT00000023290.4
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:758 → 925
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:747 → 925
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    5. XM_015132613.2 → XP_014988099.1  disks large homolog 1 isoform X11

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (8) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:712 → 879
      GuKc; Guanylate kinase homologues
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:701 → 879
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    6. XM_028843315.1 → XP_028699148.1  disks large homolog 1 isoform X10

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:702 → 880
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    7. XM_028843313.1 → XP_028699146.1  disks large homolog 1 isoform X5

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (7) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:734 → 912
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    8. XM_028843316.1 → XP_028699149.1  disks large homolog 1 isoform X10

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:702 → 880
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    9. XM_015132610.2 → XP_014988096.1  disks large homolog 1 isoform X8

      UniProtKB/TrEMBL
      A0A1D5RK14, F7FVU3
      Related
      ENSMMUP00000060658.2, ENSMMUT00000061912.2
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:714 → 892
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    10. XM_015132615.2 → XP_014988101.1  disks large homolog 1 isoform X12

      UniProtKB/TrEMBL
      F6VPG0
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:710 → 877
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:699 → 877
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_015132609.2 → XP_014988095.1  disks large homolog 1 isoform X7

      UniProtKB/TrEMBL
      F6VPG0
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:731 → 898
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:720 → 898
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    12. XM_015132603.2 → XP_014988089.1  disks large homolog 1 isoform X2

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:757 → 924
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:746 → 924
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    13. XM_015132605.2 → XP_014988091.1  disks large homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A5K1VHC7, F6VPH0, F7FVU9, H9ENR9
      Related
      ENSMMUP00000038226.3, ENSMMUT00000045209.3
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:746 → 913
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:735 → 913
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    14. XM_015132604.2 → XP_014988090.1  disks large homolog 1 isoform X3

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:753 → 920
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:742 → 920
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    15. XM_015132599.2 → XP_014988085.1  disks large homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:758 → 925
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:747 → 925
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    16. XM_015132600.2 → XP_014988086.1  disks large homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:758 → 925
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:747 → 925
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    17. XM_015132602.2 → XP_014988088.1  disks large homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:758 → 925
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:747 → 925
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    18. XM_028843325.1 → XP_028699158.1  disks large homolog 1 isoform X20

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (6) summary
      cd12031
      Location:453 → 519
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:334 → 418
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:95 → 179
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:618 → 796
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:275 → 336
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 94
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    19. XM_015132617.2 → XP_014988103.1  disks large homolog 1 isoform X16

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (7) summary
      cd12031
      Location:486 → 552
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:662 → 829
      GuKc; Guanylate kinase homologues
      smart00228
      Location:367 → 451
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:128 → 212
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:651 → 829
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:308 → 369
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 127
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    20. XM_015132616.2 → XP_014988102.1  disks large homolog 1 isoform X15

      UniProtKB/TrEMBL
      A0A5K1VHC7
      Conserved Domains (7) summary
      cd12031
      Location:499 → 565
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:675 → 842
      GuKc; Guanylate kinase homologues
      smart00228
      Location:380 → 464
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:141 → 225
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:664 → 842
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:321 → 382
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:102 → 140
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    21. XM_015132619.2 → XP_014988105.1  disks large homolog 1 isoform X18

      UniProtKB/TrEMBL
      F7FVU3
      Conserved Domains (7) summary
      cd12031
      Location:466 → 532
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:642 → 809
      GuKc; Guanylate kinase homologues
      smart00228
      Location:347 → 431
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:108 → 192
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:631 → 809
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:288 → 349
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:12 → 107
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    22. XM_028843326.1 → XP_028699159.1  disks large homolog 1 isoform X23

      Conserved Domains (3) summary
      cd12031
      Location:152 → 218
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      pfam00625
      Location:317 → 495
      Guanylate_kin; Guanylate kinase
      pfam00595
      Location:48 → 114
      PDZ; PDZ domain (Also known as DHR or GLGF)

    23. XM_028843322.1 → XP_028699155.1  disks large homolog 1 isoform X14

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:680 → 858
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    24. XM_028843320.1 → XP_028699153.1  disks large homolog 1 isoform X14

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:680 → 858
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    25. XM_028843318.1 → XP_028699151.1  disks large homolog 1 isoform X13

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:692 → 870
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    26. XM_028843321.1 → XP_028699154.1  disks large homolog 1 isoform X14

      UniProtKB/TrEMBL
      F6VPE3
      Related
      ENSMMUP00000021794.4, ENSMMUT00000023293.4
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:680 → 858
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    27. XM_028843319.1 → XP_028699152.1  disks large homolog 1 isoform X13

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:549 → 615
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:430 → 514
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:692 → 870
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:371 → 432
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    28. XM_028843314.1 → XP_028699147.1  disks large homolog 1 isoform X9

      UniProtKB/TrEMBL
      A0A1D5REU1, F6VPG0, H9ENS0
      Conserved Domains (7) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:713 → 891
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    29. XM_015132611.2 → XP_014988097.1  disks large homolog 1 isoform X9

      UniProtKB/TrEMBL
      A0A1D5REU1, F6VPG0, H9ENS0
      Conserved Domains (7) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:713 → 891
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    30. XM_015132621.2 → XP_014988107.1  disks large homolog 1 isoform X22

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:466 → 532
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:608 → 775
      GuKc; Guanylate kinase homologues
      smart00228
      Location:347 → 431
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:108 → 192
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:597 → 775
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:288 → 349
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:12 → 107
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    31. XM_015132620.2 → XP_014988106.1  disks large homolog 1 isoform X21

      UniProtKB/TrEMBL
      F6VPE3
      Conserved Domains (7) summary
      cd12031
      Location:466 → 532
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:620 → 787
      GuKc; Guanylate kinase homologues
      smart00228
      Location:347 → 431
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:108 → 192
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:609 → 787
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:288 → 349
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:12 → 107
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    32. XM_028843324.1 → XP_028699157.1  disks large homolog 1 isoform X19

      UniProtKB/TrEMBL
      F6VPG0
      Conserved Domains (6) summary
      cd12031
      Location:499 → 565
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:380 → 464
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:141 → 225
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:630 → 808
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:321 → 382
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:110 → 140
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    33. XM_015132618.2 → XP_014988104.1  disks large homolog 1 isoform X17

      UniProtKB/TrEMBL
      F6VPG0
      Conserved Domains (7) summary
      cd12031
      Location:499 → 565
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:653 → 820
      GuKc; Guanylate kinase homologues
      smart00228
      Location:380 → 464
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:141 → 225
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:642 → 820
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:321 → 382
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:102 → 140
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    34. XM_015132608.2 → XP_014988094.1  disks large homolog 1 isoform X6

      UniProtKB/TrEMBL
      F6VPG0
      Conserved Domains (8) summary
      cd12031
      Location:582 → 648
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00072
      Location:736 → 903
      GuKc; Guanylate kinase homologues
      smart00228
      Location:463 → 547
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:725 → 903
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:4 → 62
      L27_1; L27_1
      pfam10600
      Location:404 → 465
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    Nucleotide Protein
    Heading Accession and Version

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