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    PRUNE2 prune homolog 2 with BCH domain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707402, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRUNE2provided by VGNC
    Official Full Name
    prune homolog 2 with BCH domainprovided by VGNC
    Primary source
    VGNC:VGNC:76314
    See related
    Ensembl:ENSMMUG00000001043
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PRUNE2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (92017478..92311328, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (92869039..93162450, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene glucosaminyl (N-acetyl) transferase 1 Neighboring gene riboflavin kinase Neighboring gene uncharacterized LOC106993801 Neighboring gene uncharacterized LOC114672820 Neighboring gene ATP synthase subunit f, mitochondrial pseudogene Neighboring gene forkhead box B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyrophosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein prune homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      92017478..92311328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117923.2 → XP_014973409.2  protein prune homolog 2 isoform X10

      UniProtKB/TrEMBL
      G7NGD2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    2. XM_015117926.2 → XP_014973412.2  protein prune homolog 2 isoform X3

      UniProtKB/TrEMBL
      G7NGD2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2908
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2910 → 3031
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    3. XM_015117929.2 → XP_014973415.2  protein prune homolog 2 isoform X6

      UniProtKB/TrEMBL
      A0A5F8AD03
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2901
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2913 → 3034
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    4. XM_015117924.2 → XP_014973410.2  protein prune homolog 2 isoform X1

      UniProtKB/TrEMBL
      G7NGD2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2901
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2913 → 3034
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    5. XM_015117936.2 → XP_014973422.2  protein prune homolog 2 isoform X16

      UniProtKB/TrEMBL
      A0A5F8A510, A0A5F8AL90
      Related
      ENSMMUP00000078602.1, ENSMMUT00000097831.1
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2909
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2911 → 3032
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    6. XM_015117931.2 → XP_014973417.2  protein prune homolog 2 isoform X8

      UniProtKB/TrEMBL
      A0A5F8AD03, F6SAX4
      Related
      ENSMMUP00000001396.4, ENSMMUT00000001485.4
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2909
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2911 → 3032
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    7. XM_015117925.2 → XP_014973411.2  protein prune homolog 2 isoform X2

      UniProtKB/TrEMBL
      G7NGD2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2909
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2911 → 3032
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    8. XM_015117935.2 → XP_014973421.2  protein prune homolog 2 isoform X15

      UniProtKB/TrEMBL
      A0A5F8A510
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    9. XM_015117932.2 → XP_014973418.2  protein prune homolog 2 isoform X11

      UniProtKB/TrEMBL
      A0A5F8AD03
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    10. XM_028835264.1 → XP_028691097.1  protein prune homolog 2 isoform X13

      UniProtKB/TrEMBL
      A0A5F8A510
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    11. XM_015117934.2 → XP_014973420.2  protein prune homolog 2 isoform X14

      UniProtKB/TrEMBL
      A0A5F8A510
      Related
      ENSMMUP00000073034.1, ENSMMUT00000080277.1
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    12. XM_015117928.2 → XP_014973414.2  protein prune homolog 2 isoform X5

      UniProtKB/TrEMBL
      A0A5F8AD03
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    13. XM_028835263.1 → XP_028691096.1  protein prune homolog 2 isoform X9

      UniProtKB/TrEMBL
      A0A5F8A510
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    14. XM_015117930.2 → XP_014973416.2  protein prune homolog 2 isoform X7

      UniProtKB/TrEMBL
      G7NGD2
      Related
      ENSMMUP00000074846.1, ENSMMUT00000092893.1
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2909
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2911 → 3032
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    15. XM_015117927.2 → XP_014973413.2  protein prune homolog 2 isoform X4

      UniProtKB/TrEMBL
      G7NGD2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2902
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2914 → 3035
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    16. XM_015117933.2 → XP_014973419.2  protein prune homolog 2 isoform X12

      UniProtKB/TrEMBL
      G7NGD2
      Related
      ENSMMUP00000049196.2, ENSMMUT00000067979.2
      Conserved Domains (3) summary
      COG1227
      Location:24 → 278
      PPX1; Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion, Inorganic ion transport and metabolism]
      pfam12496
      Location:2792 → 2908
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
      pfam13716
      Location:2910 → 3031
      CRAL_TRIO_2; Divergent CRAL/TRIO domain
    Nucleotide Protein
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