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    AFDN afadin, adherens junction formation factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693560, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AFDNprovided by VGNC
    Official Full Name
    afadin, adherens junction formation factorprovided by VGNC
    Primary source
    VGNC:VGNC:69818
    See related
    Ensembl:ENSMMUG00000021044
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See AFDN in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (2688655..2830526, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (169274271..169416161)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 25 Neighboring gene putative uncharacterized protein KIF25-AS1 Neighboring gene skin secretory protein xP2 Neighboring gene uncharacterized LOC114677437 Neighboring gene uncharacterized LOC114677436 Neighboring gene putative uncharacterized protein AFDN-DT Neighboring gene uncharacterized LOC114677438

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of protein localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    afadin
    Names
    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      2688655..2830526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137697.2 → XP_014993183.2  afadin isoform X4

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 939
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1466 → 1699
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1015 → 1097
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    2. XM_028846970.1 → XP_028702803.1  afadin isoform X22

      UniProtKB/TrEMBL
      F7HG08
      Related
      ENSMMUP00000027697.4, ENSMMUT00000029596.4
      Conserved Domains (6) summary
      cd00060
      Location:385 → 485
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:597 → 925
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
      pfam00595
      Location:1001 → 1083
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam15709
      Location:1452 → 1673
      DUF4670; Domain of unknown function (DUF4670)

    3. XM_015137704.2 → XP_014993190.2  afadin isoform X13

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:385 → 485
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:597 → 925
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1452 → 1685
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1001 → 1083
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    4. XM_015137710.2 → XP_014993196.2  afadin isoform X20

      UniProtKB/TrEMBL
      F7HG08
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 933
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1460 → 1679
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1009 → 1091
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    5. XM_015137701.2 → XP_014993187.2  afadin isoform X9

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 933
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1460 → 1693
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1009 → 1091
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    6. XM_015137708.2 → XP_014993194.2  afadin isoform X18

      UniProtKB/TrEMBL
      F7HG08
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1686
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    7. XM_015137703.2 → XP_014993189.2  afadin isoform X12

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1686
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    8. XM_028846968.1 → XP_028702801.1  afadin isoform X17

      UniProtKB/TrEMBL
      F7HG08
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1688
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    9. XM_015137702.2 → XP_014993188.2  afadin isoform X11

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1688
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    10. XM_028846966.1 → XP_028702799.1  afadin isoform X8

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam17380
      Location:1417 → 1694
      DUF5401; Family of unknown function (DUF5401)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    11. XM_015137696.2 → XP_014993182.2  afadin isoform X3

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1699
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    12. XM_015137699.2 → XP_014993185.2  afadin isoform X6

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam17380
      Location:1417 → 1695
      DUF5401; Family of unknown function (DUF5401)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    13. XM_015137706.2 → XP_014993192.2  afadin isoform X16

      UniProtKB/TrEMBL
      F7HG07, G7MR78
      Related
      ENSMMUP00000027696.4, ENSMMUT00000029595.4
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1700
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    14. XM_015137698.2 → XP_014993184.2  afadin isoform X5

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1700
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    15. XM_015137694.2 → XP_014993180.2  afadin isoform X1

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:418 → 500
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:612 → 940
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1467 → 1700
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1016 → 1098
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:248 → 348
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 132
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    16. XM_015137713.2 → XP_014993199.2  afadin isoform X23

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:383 → 483
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:595 → 916
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      cd01781
      Location:246 → 346
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
      pfam00595
      Location:992 → 1074
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam15709
      Location:1443 → 1664
      DUF4670; Domain of unknown function (DUF4670)

    17. XM_015137705.2 → XP_014993191.2  afadin isoform X15

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:383 → 483
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:595 → 916
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      cd01781
      Location:246 → 346
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
      pfam00595
      Location:992 → 1074
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam15709
      Location:1443 → 1676
      DUF4670; Domain of unknown function (DUF4670)

    18. XM_015137700.2 → XP_014993186.2  afadin isoform X7

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:416 → 498
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:610 → 938
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1465 → 1698
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1014 → 1096
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:246 → 346
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    19. XM_028846969.1 → XP_028702802.1  afadin isoform X21

      UniProtKB/TrEMBL
      F7HG08
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 932
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1459 → 1678
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1008 → 1090
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    20. XM_015137712.2 → XP_014993198.2  afadin isoform X14

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 932
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1459 → 1678
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1008 → 1090
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    21. XM_015137709.2 → XP_014993195.2  afadin isoform X19

      UniProtKB/TrEMBL
      F7HG08
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 932
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1459 → 1680
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1008 → 1090
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    22. XM_028846967.1 → XP_028702800.1  afadin isoform X10

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 932
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1459 → 1692
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1008 → 1090
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

    23. XM_015137695.2 → XP_014993181.2  afadin isoform X2

      UniProtKB/TrEMBL
      F7HG05
      Conserved Domains (6) summary
      cd00060
      Location:417 → 499
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15471
      Location:611 → 939
      Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
      pfam15709
      Location:1466 → 1699
      DUF4670; Domain of unknown function (DUF4670)
      pfam00595
      Location:1015 → 1097
      PDZ; PDZ domain (Also known as DHR or GLGF)
      cd01781
      Location:247 → 347
      RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
      cd01782
      Location:20 → 131
      RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    Nucleotide Protein
    Heading Accession and Version

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